1. Farcal L.R., Uboldi C., Mehn D., Giudetti G., Nativo P., Ponti J., Gilliland D., Rossi F., Bal-Price
A., 2013, Mechanisms of toxicity induced by SiO2 nanoparticles of in vitro human alveolar barrier:
effects on cytokine production, oxidative stress induction, surfactant proteins A mRNA expression
and nanoparticles uptakeVol. 7 (6): 1095-1110
2. Farcal R.L, L. Mandru, N.A. Oros, 2009, Heavy metals residues in animal products, in
Maramures County during 1997-200866 (1-2): 135-140 3. Oros N.A., L. Farcal, A. Chereji, 2009, Pollution of soil and water with lead, zinc and cadmium in
4. Farcal R.L, N.A. Oros, D. Desmecht, 2008, Effect of respiratory exposure to bentonite dust on the
severity of pneumovirus primoinfection in a mouse model, 14 (4): 419-430 5. Sevastre B., L. Farcal, I. Prodan, I. Marcus, M. Tamas, C. Deliu, 2008, Peucedanum oreoselinum
l. moench effect in Ehrlich ascitic carcinoma65(1): 144-148 6. Farcal R.L., C. Bidian, C. Catoi, V. Rus, A. Oros, I. Marcus, A. Pop, 2007, The evaluation of
experimental respiratory exposure methods, with bentonite particles, on Wistar rats, 64: 136-141 7. Farcal R.L., C. Bidian, C. Catoi, V.I. Rus, A. Oros, I. Marcus, A. Pop, 2007, Respiratory exposure
to bentonite particles on rat – histopathological and cytological evaluation234-241 8. Farcal R.L., A. Thomas, M. Palm, N.A. Oros, I. Marcus, D. Desmecht, 2007, The obtaining of a
primary cell culture from pig’s tracheal or bronchial epithelium, RevRomMedVet, Vol.17 (3) 9. Bidian C., L. Farcal, S. Tache, R Moldovan, N. Decea, 2007, Experimental study regarding the
influence of particulate air pollutants on oxidants/antioxidants balance,64
(1-2): 62-67
10. Oros N.A., R.L. Farcal, A. Marculescu, M. Cernea, G.A. Bale, 2007, Clinical, paraclinical and
therapeutic evaluations of acetaminophen toxicosis in dogs,64 (1-2): 514-520 11. Oros, N. A., Marculescu, A., Marcus, I. B., Farcal, L., Bale, G. A., 2005, The surveillance of
organochlorinated pesticides and heavy metals residues in animal products, along the Harghita County, during 1999-2004 period62: 237-239 12. Oros, A., Marcus, I., Farcal, L., Bale, G. A., Marculescu, A., 2005, Researches concerning the
serum, urinary and tissue levels of lead and aluminium on cows with osteomalacia, 62: 233-236 13. Marcus I., L. Farcal, A. Pop, B. Sevastre, M. Duma, A. Oros, 2005, The deuterium-depleted water
intake correlated with the values of some haematological, biochemical and gravimetric parameters in NMRI mice inoculated with a transplantable tumor (Ehrlich Ascite), 62: 172-178 14. Marcus, I.,Pop, A., Farcal, L., Farcau, O., Oros, A., 2002, The implementation of a model of
experimental depression in laboratory animals in order to study its consequences on the development of the ehrlich ascite transplantable tumor: Clinical and behavioral aspects.,57-58: 684-691 1. 9th International Conference and Workshop on Biological Barriers – in vitro and in silico tools for
drug delivery and nanosafety research, 5-9 March 2012, Saarbrücken, Germany
- Oral presentation and poster "The response of an in vitro human alveolar barrier to SiO2
nanoparticles exposure in the presence or absence of THP-1 monocytes" 2. EPAA / ECVAM Workshop "Potential for further integration of toxicokinetic modeling into the
prediction of in vivo dose-response curves without animal experiments", 13-14 October 2011,
Ispra, Italy
3. European Respiratory Society Annual Congress, 18-22 September 2010, Barcelona, Spain
- Poster Characterization of an in-vitro co-culture model for the human alveolar barrier
(European Respiratory Journal -Volume 36, Supplement 54, 2010) 4. 11th DKMT Regional Conference on Environment and Health, 15-16 May 2009, Szeged, Hungary
- PosterEffect of respiratory exposure to bentonite dust on the severity of pneumovirus
primoinfection in a mouse model5. Central and Eastern European Conference on Health and the Environment - CEECHE, October
19-22, 2008 Cluj-Napoca, Romania
6. International Conference of Cellular and Tissue Comparative Pathology, 3-5 July 2008, Cluj-
- Oral presentationUsing an in vitro model for studying the biological effects of bentonite
7. Seminar International USAMV Cluj-Napoca, “The Romanian scientific research in the area of
cellular and tissue compared pathophysiology”, November 2006, Cluj-Napoca, Romania
- Oral presentationContribution of atmospheric pollutants in development and severity of
1. N.A. Oros, L.R. Farcal, A. Chereji, “Residues of organochlorinated pesticides in milk and dairy
products, in Cluj County during 1997-2007”Cluj-Napoca, Romania, 2009
2. E. Forti, S. Salovaar, L. Farcal, Y. Cetin, A. Bulgheroni, W. Pfaller, P. Prieto „In Vitro study of the
toxicity induced by Nickel and Cobalt particles on human lung cells”, 15th Congress on
Alternatives to Animal Testing, Linz, Austria, 2008
3. Oros N.A., R.L. Farcal, A. Marculescu, M. Cernea, “The surveillance of organochlorinated
pesticides and heavy metals residues in animals’ products, between 2001 and 2005 in Mures
”Cluj-Napoca, Romania, 2007



Hindawi Publishing CorporationJournal of ObesityVolume 2010, Article ID 831901, 6 pagesdoi:10.1155/2010/831901 Clinical Study Long-Term Effects of Metformin and Lifestyle Modification onNonalcoholic Fatty Liver Disease Obese AdolescentsLian Tock,1 Ana R. Dˆamaso,1, 2 Aline de Piano,1 June Carnier,1 Priscila L. Sanches,1Henrique Manoel Lederman,3 Regina M. Y. Ernandes,4 Marco T ´ulio de Mello,4

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