Microsoft word - clindoxyl pi-2004-3.doc
CLINDOXYL GEL (logo) (Clindamycin 1% and benzoyl peroxide 5%) TOPICAL ACNE THERAPY CLINDOXYL® Gel (clindamycin phosphate and benzoyl peroxide) ACTION AND CLINICAL PHARMACOLOGY Clindamycin Phosphate Although clindamycin phosphate is inactive in vitro , rapid in vivo hydrolysis converts this compound to the active antibiotic clindamycin. Like other macrolides, clindamycin