Microsoft word - casolaro cv.doc

Name Vincenzo Casolaro Citizenship Italy U.S. Immigration Status Permanent Resident Education and Training 1980-86 M.D., Federico II University, Naples, Italy Intern, Department of Medicine, Federico II University Resident, Postgraduate Program of Clinical Immunology and Allergology, University of (7/15-9/15) Postdoctoral Fellow, Division of Clinical Immunology, Johns Hopkins University, Good Samaritan Hospital, Baltimore, MD 1989-92 Postdoctoral Fellow, Division of Clinical Immunology and Allergology, Federico II 1990-94 Ph.D., Postgraduate Program of Cardiovascular Pathophysiology, Tor Vergata Postdoctoral Fellow, Division of Clinical Immunology, Johns Hopkins University Unrestricted licence to practice of Medicine and Surgery in the European Community, Federico II University Foreign Medical Graduate Examination in the Medical Sciences, Basic and Clinical Science components European board in Clinical Immunology and Allergology Chronology of Employment 1996-99 Visiting Assistant Professor, Division of Clinical Immunology, Johns Hopkins At-term Professor, Postgraduate Program of Clinical Immunology, Federico II University Senior Investigator, Laboratory of Hematology and Oncology, Chief Institute of Health, 1998-99 Visiting Scientist, Kimmel Cancer Research Institute, Thomas Jefferson University, Assistant Professor of Medicine, Division of Allergy and Clinical Immunology, Johns Hopkins University Italian Society of Allergy and Clinical Immunology (SIAIC) Italian Society of Immunology and Immunopathology (SIII) American Academy of Allergy, Asthma and Immunology (AAAAI) Extended Scholarship Award, the UCB Institute of Allergy, Brussels, Belgium Essex Award, the Italian Society of Allergy and Clinical Immunology, Milan, Italy Investigator Award, National AIDS Association (ANLAIDS), Rome, Italy Research fellowship, National Research Council (CNR), Rome, Italy Fogarty International Fellowship, Public Health Service, Bethesda, MD Marion-Merrell Dow Scholar in Allergy, American Academy of Allergy, Asthma and Immunology, Milwaukee, WI Schering-Plough International AThe Respiratory 2000 International Young Investigator Award,@ Kenilworth, NJ Asthma and Allergy Foundation of America Investigator Award, Washington, DC Exploratory Research Award Program, Uniformed Services University of the Health Sciences, American Journal of Respiratory Cell and Molecular Biology Experimental Biology and Medicine Proceedings of the National Academy of Sciences of the USA The Journal of Allergy and Clinical Immunology The Journal of Biological Chemistry Funding 1997-03 National Institute of Allergy and Infectious Disease (NIAID), NIH, Research Grant, Principal Investigator, Regulation of IL-4 in Cells Involved in Allergic Disease, R29 AI41463 Research Grant, Co-Investigator, Regulation of C-C Chemokines in Human Airway Epithelium, R01 AI44242 2001-03 American Heart Association Mid-Atlantic Affiliate, Grant-in-Aid Award, Principal Investigator, Inhibition of Interleukin-4 Expression by Aspirin: Definition of Novel Molecular Targets of Anti-inflammatory Salicylates, AHA 0151500U 2003-07 NIAID, NIH, Research Grant, Principal Investigator, Regulation of IL-4 in Cells Involved in Allergic Disease, R01 AI041463 2003-07 National Heart, Lung and Blood Institute (NHLBI), NIH, Research Grant, Co- Investigator, Yin-Yang-1: a Novel Transcription Factor in Th Responses, R01 HL073952 NIAID, NIH, Research Grant, Co-Investigator, Immunogenetic Analysis of Immune Response to Allergens, R01 AI052468 NIAID, NIH, Research Grant, Co-Investigator, Bronchial Epithelial Cell Costimulation of CD4+ T Cells, R21 AI059711 NIAID, NIH, Research Grant, Co-Investigator, RNA-binding Protein HuR in Allergic Inflammation, R01 AI060990 NHLBI, NIH, Research Grant, Co-Investigator, Resolution of Asthma Exacerbations in the Inner City Invited Speaker, 19th National Meeting, SIAIC, Bari, Italy Invited Speaker, Annual Meeting, SIAIC, Ancona, Italy Invited Speaker, Workshop on The Genetics of Asthma, Down Hall, UK Invited Speaker, Annual Meeting, SIAIC, Santa Margherita di Pula, Italy Invited Speaker, 20th National Meeting, SIAIC, Rome, Italy Invited Speaker, Annual Meeting, SIAIC, Naples, Italy Invited Speaker, Workshop on Transcription Factors Regulating IL-4 and ε Gene Expression, European Science Foundation, Florence, Italy Invited Speaker, Respiratory 2000 International Award Ceremony, Schering-Plough, Kenilworth, NJ Invited Speaker, 3rd International Consensus Conference on Allergology and Clinical Immunology, Rome, Italy Invited Speaker, V International Asthma Conference, Ischia, Italy Invited Speaker, Division of Allergy and Clinical Immunology, La Sapienza University School of Medicine, Rome, Italy Invited Speaker, II International Symposium on Occupational and Environmental Allergy and Immune Diseases, Chieti, Italy Paper Alert Editorial Board Member, Current Opinion in Immunology Seminar Co-Chair, 57th Annual Meeting, AAAAI, New Orleans, LO Doctoral Committee Member, Johns Hopkins University, School of Hygiene and Public Health Faculty and Contact, International Doctorate Program in Molecular Oncology and Endocrinology, Federico II University, Johns Hopkins University Managing Editor, Frontiers in Bioscience Seminar Co-Chair, 58th Annual Meeting, AAAAI, New York, NY Invited Speaker, 60th Annual Meeting, AAAAI, San Francisco, CA Research Conference Coordinator, Division of Allergy and Clinical Immunology, Johns Hopkins University Invited Speaker, Immunology Council Seminar Series, Johns Hopkins University Doctoral Committee Member, Federico II University, School of Medicine and Surgery Invited Speaker, Scientific Seminar Series, Second University of Naples, Naples, Italy Secretary, Johns Hopkins Immunology Council, Johns Hopkins University 1. Casolaro V., Galeone D., Giacummo A., Sanduzzi A., Melillo G., Marone G.: Human
basophil/mast cell releasability. V. Functional comparisons of cells obtained from peripheral blood, lung parenchyma, and bronchoalveolar lavage in asthmatics. American Review of Respiratory Disease 1989; 139:1375-1382. 2. Casolaro V., Cirillo R., Genovese A., Formisano S., Ayala F., Marone G.: Human basophil
releasability. IV. Changes in basophil releasability in patients with chronic urticaria. Journal of Immunological Research 1989; 1:67-73. 3. Marone G., Casolaro V., Paganelli R., Quinti I.: IgG anti-IgE from atopic dermatitis induces
mediator release from basophils and mast cells. The Journal of Investigative Dermatology 1989; 93:246-252. 4. Marone G., Petracca R., Vigorita S., Casolaro V.: Adenosine receptors of human leukocytesBII:
Characterization of an inhibitory P-site. Biochemical Pharmacology 1990; 40:1963-1973. 5. Casolaro V., Spadaro G., Marone G.: Human basophil releasability. VI. Changes in basophil
releasability in patients with allergic rhinitis or bronchial asthma. American Review of Respiratory Disease 1990; 142:1108-1111. 6. Patella V., Casolaro V., Björck L., Marone G.: Protein L: a bacterial Ig-binding protein that
activates human basophils and mast cells. The Journal of Immunology 1990; 145:3054-3061. 7. Columbo M., Casolaro V., Warner J.A., MacGlashan D.W., Jr., Kagey-Sobotka A., Lichtenstein
L.M.: The mechanism of mediator release from human basophils induced by platelet-activating factor (PAF). The Journal of Immunology 1990; 145:3855-3861. 8. Genovese A., Petracca R., Vigorita S., Casolaro V., Marone G.: Adenosine receptors on human
leukocytes. III. Characterization of an A2/Ra receptor. Journal of Immunological Research 1991; 9. Stellato C., Casolaro V., Ciccarelli A., Mastronardi P., Mazzarella B., Marone G.: General
anaesthetics induce only histamine release selectively from human mast cells. British Journal of Anaesthesia 1991; 67:751-758. 10. Stellato C., de Paulis A., Ciccarelli A., Cirillo R., Patella V., Casolaro V., Marone G.: Anti-
inflammatory effect of cyclosporin A on human skin mast cells. The Journal of Investigative Dermatology 1992; 98:800-804. 11. Stellato C., Cirillo R., de Paulis A., Casolaro V., Patella V., Mastronardi P., Mazzarella B.,
Marone G.: Human basophil/mast cell releasability. IX. Heterogeneity of the effects of opioids on mediator release. Anesthesiology 1992; 77:932-940. 12. Marone G., Petracca R., Vigorita S., Genovese A., Casolaro V.: Adenosine receptors on human
leukocytes. IV. Characterization of an A1/Ri receptor. International Journal of Clinical & Laboratory Research 1992; 22:235-242. 13. Casolaro V., Spadaro G., Patella V., Marone G.: In vivo characterization of the anti-
inflammatory effect of cyclosporin A on human basophils. The Journal of Immunology 1993; 151:5563-5573. 14. Casolaro V., Meliota S., Marino O., Patella V., de Paulis A., Guidi G., Marone G.: Nimesulide,
a sulfonanilide non-steroidal anti-inflammatory drug, inhibits mediator release from human basophils and mast cells. The Journal of Pharmacology and Experimental Therapeutics 1993; 267:1375-1385. 15. Patella V., Casolaro V., Ciccarelli A., Pettit G.R., Columbo M., Marone G.: The antineoplastic
bryostatins affect human basophils and mast cells differently. Blood 1995; 85:1272-1281. 16. Casolaro V., Georas S.N., Song Z., Zubkoff I.D., Abdulkadir S.A., Thanos D., Ono S.J.:
Inhibition of NF-AT-dependent transcription by NF-κB: Implications for differential gene expression in T helper cell subsets. Proceedings of the National Academy of Sciences of the United States of America 1995; 92:11623-11627. 17. Song Z., Casolaro V., Chen R., Georas S.N., Monos D., Ono S.J.: Polymorphic nucleotides
within the human IL-4 promoter that mediate overexpression of the gene. The Journal of Immunology 1996; 156:424-429. 18. Abdulkadir S.A., Casolaro V., Tai A.K.-F., Thanos D., Ono S.J.: High mobility group I/Y
protein functions as a specific cofactor for Oct-2A: Mapping of interaction domains. Journal of Leukocyte Biology 1998; 64:681-691. 19. Georas S.N., Cumberland J.E., Burke T.F., Chen R., Schindler U., Casolaro V.: Stat6 inhibits
human interleukin-4 promoter activity in T cells. Blood 1998; 92:4529-4538. 20. Matsukura S., Stellato C., Plitt J.R., Bickel C., Miura K., Georas S.N., Casolaro V., Schleimer
R.P.: Activation of eotaxin gene transcription by nuclear factor kappa B (NF-κB) and signal transducer and activator of transcription 6 (STAT6) in human airway epithelial cells. The Journal of Immunology 1999; 163:6876-6883. 21. Chen R., Burke T., Cumberland J., Brummet M., Beck L., Casolaro V., Georas S.:
Glucocorticoids inhibit calcium- and calcineurin-dependent activation of the human IL-4 promoter. The Journal of Immunology 2000; 164:825-832. 22. Nickel R.G., Casolaro V., Wahn U., Beyer K., Barnes K.C., Plunkett B.S., Freidhoff L.F.,
Sengler C., Plitt J.R., Schleimer R.P., Caraballo L., Naidu R.P., Levett P.N., Beaty T.H., Huang S.-K.: Atopic dermatitis is associated with a functional mutation in the promoter of the CC chemokine RANTES. The Journal of Immunology 2000; 164:1612-1616. 23. Georas S.N., Cumberland J.E., Burke T.F., Park E., Ono S.J., Casolaro V.: Characterization of a
novel negative regulatory element in the human interleukin 4 promoter. Leukemia 2000; 14:629-635. 24. Burke T.F., Casolaro V., Georas S.N.: Characterization of P5, a novel NFAT/AP-1 site in the
human IL-4 promoter. Biochemical and Biophysical Research Communications 2000; 270:1016-1023. 25. Kim J., Sanders S.P., Siekierski E.S., Casolaro V., Proud D.: Role of NF-κB in cytokine
production induced from human airway epithelial cells by rhinovirus infection. The Journal of Immunology 2000; 165:3384-3392. 26. Casolaro V., Keane-Myers A.M., Swendeman S.L., Steindler C., Zhong F., Sheffery M., Georas
S.N., Ono S.J.: Identification and characterization of a critical CP2-binding element in the human IL-4 promoter. The Journal of Biological Chemistry 2000; 275:36605-36611. 27. Barnes K.C., Mathias R.A., Nickel R., Freidhoff L.R., Stockton M.L., Xue X., Naidu R.P., Levett P.N., Casolaro V., Beaty T.H.: Testing for gene-gene interaction controlling total IgE in
families from Barbados: Evidence of sensitivity regarding linkage heterogeneity among families.
Genomics 2001; 71:246-251.
28. Cianferoni A., Schroeder J.T., Kim J., Schmidt J.W., Lichtenstein L.M., Georas S.N., Casolaro
V.: Selective inhibition of IL-4 gene expression in human T cells by aspirin. Blood 2001;
97:1742-1749.
29. Matsukura S., Stellato C., Georas S.N., Casolaro V., Plitt J.R., Miura K., Kurosawa S.,
Schindler U., Schleimer R.P.: Interleukin-13 upregulates eotaxin expression in airway epithelial cells by a STAT6-dependent mechanism. American Journal of Respiratory Cell and Molecular Biology 2001; 24:755-761. 30. Guo J., Casolaro V., Seto E., Yang W.M., Chang C., Seminario M.C., Keen J., Georas S.N.:
Yin-Yang 1 activates interleukin-4 gene expression in T cells. The Journal of Biological Chemistry 2001; 276:48871-48878. 31. Valapour M., Guo J., Keen J., Schroeder J.T., Cianferoni A., Casolaro V., Georas S.N.: Histone
deacetylation inhibits IL-4 gene expression in T cells. The Journal of Allergy and Clinical 32. Schroeder J.T., Miura K., Kim H.H., Sin A., Cianferoni A., Casolaro V.: Selective expression of
nuclear factor of activated T cells (NFAT)-2/c1 in human basophils: evidence for involvement in IgE-mediated IL-4 generation. The Journal of Allergy and Clinical Immunology 2002; 109:507-513. 33. Vonakis B.M., Sora R., Langdon J.M., Casolaro V., MacDonald S.M.: Inhibition of cytokine
gene transcription by the human recombinant histamine releasing factor (HrHRF) in human T lymphocytes. Journal of Immunology 2003; 171:3742-3750. 34. Atasoy U., Curry S.L., López de Silanes I., Shyu A.B., Casolaro V., Gorospe M., Stellato C.:
Regulation of eotaxin gene expression by TNFα and IL-4 through messenger RNA stabilization. Journal of Immunology 2003; 171:4369-4378. 35. Saatian B., Yu X.Y., Lane A.P., Doyle T., Casolaro V., Spannhake E.W.: Expression of genes
for B7-H3 and other T cell ligands by nasal epithelial cells during differentiation and activation. American Journal of Physiology: Lung Cellular and Molecular Physiology 2004; 287:L217-L225. 36. Rubenfeld J., Guo J., Sookrung N., Chen R., Chaicumpa W., Casolaro V., Zhao Y., Natarajan
V., Georas S.: Lysophosphatidic acid enhances interleukin-13 gene expression and promoter activity in T-cells. American Journal of Physiology: Lung Cellular and Molecular Physiology 2006; 290:L66-74. 37. Keen J.C., Cianferoni A., Florio G., Guo J., Chen R., Wills-Karp M., Casolaro V., Georas S.N.:
Characterization of a novel PMA-inducible pathway of IL-13 gene expression in T cells. Immunology 2006; 117:29-37. 1. Ayala F., Balato N., Lembo G., Cirillo R., Casolaro V., Marone G.: The relevance of
releasability of chemical mediators in the pathogenesis of allergic disorders. Italian General Review of Dermatology 1987; 24:147-157. 2. Marone G., Casolaro V., Cirillo R., Condorelli M.: Heterogeneity of human mast cells and
basophils. The Italian Journal of Medicine 1988; 4:124-129. 3. Marone G., Casolaro V., Cirillo R., Stellato C., Genovese A.: Pathophysiology of human
basophils and mast cells in allergic disorders. Clinical Immunology and Immunopathology 1989; 50:S24-S40. 4. Marone G., Casolaro V.: Is there a role for anti-IgE autoantibodies in the pathogenesis of human
inflammatory diseases? (editorial). Journal of Immunological Research 1989; 3:105-110. 5. Casolaro V.: Modulation of mediator release from human primary effector cells by platelet-
activating factor. Allergy & Clinical Immunology News 1991; 3:20-23. 6. Marone G., Casolaro V., Stellato C., de Paulis A., Genovese A.: Immunological and
pharmacological heterogeneity of human FcεRI+ cells. Journal of Chemotherapy 1991; 3:55-58. 7. Marone G., de Paulis A., Ciccarelli A., Casolaro V., Cirillo R.: Mechanism(s) of action of
cyclosporin A. Seminars in Clinical Immunology 1991; 2:11-16. 8. Stellato C., Casolaro V., Ciccarelli A., de Crescenzo G., Patella V., Marone G.: Selective
activation of human mast cells by general anesthetics. Agents and Actions 1992; 35:C191-C194. 9. Marino O., Casolaro V., Meliota S., Stellato C., Guidi G., Marone G.: Inhibition of histamine
release from human FcεRI+ cells by nimesulide. Agents and Actions 1992; 35:C311-C314. 10. Marone G., de Paulis A., Casolaro V., Ciccarelli A., Spadaro G., Cirillo R.: In vitro and in vivo
characterization of the anti-inflammatory effects of cyclosporin A. International Archives of Allergy and Immunology 1992; 99:279-283. 11. Stellato C., Casolaro V., Renda A., Genovese A., Marone G.: Anti-inflammatory effect of
deflazacort. International Archives of Allergy and Immunology 1992; 99:340-342. 12. Triggiani M., Casolaro V., Genovese A., Spadaro G., Marone G.: Heterogeneity of human
FcεRI-bearing cells. Annals of Allergy 1993; 71:133-138. 13. Casolaro V., Georas S.N., Marone G., Ono S.J.: Molecular mechanisms controlling interleukin-
4 synthesis. Forme 1996; 7:11-19. 14. Casolaro V., Georas S.N., Song Z., Ono S.J.: Biology and genetics of atopic disease. Current
Opinion in Immunology 1996; 8:796-803. 15. Casolaro V., Steindler C., Georas S.N., Ono S.J.: Molecular mechanisms of interleukin-4
production. International Journal of Immunopathology and Pharmacology 1997; 10:1-5. 16. Marone G., Casolaro V., Patella V., Florio G., Triggiani M.: Molecular and cellular biology of
mast cells and basophils. International Archives of Allergy and Immunology 1997; 114:207-217. 17. Keane-Myers A., Casolaro V., Ono S.J.: Molecular basis and role of differential cytokine
production in T helper cell subsets in immunologic disease. Advances in Experimental Medicine and Biology 1998; 438:479-484. 18. Casolaro V., Cianferoni A., Georas S.N.: The molecular basis of IL-4 dysregulation in the atopic
condition. International Journal of Immunopathology and Pharmacology 1999; 12:33-35. 19. Elliott T., Bonneville M., Kruisbeek A., van Halem M.A., Walker P.R., Casolaro V.,
Glaichenhaus N., Vyakarnam A., Casanova J.-L., Liu Y., Adkis C., Green A.: Immunology. Current Opinion in Immunology 2001; 13:255-264. 20. Georas S.N., Guo J., De Fanis U., Casolaro V.: T-helper cell type-2 regulation in allergic
disease. European Respiratory Journal 2005; 26:1119-1137. 1. Marone G., Casolaro V., Quinti I., Paganelli R., Spadaro G., Stellato C.: Mast cell and basophil
activation by human anti-IgE autoantibodies. In: Progress in Allergy and Clinical Immunology (W.J. Pichler, B.M. Stadler, C. Dahinden, A.R. Pécoud, P.C. Frei, C. Schneider, A.L. de Weck, eds.). Hogrefe & Huber Publishers, Seattle, Toronto, Bern, Göttingen, 1989, pp. 125-128. 2. Casolaro V., Stellato C., Spadaro G., Marone G.: Alterations of immunoregulation in allergic
diseases. In: Immunoregulation and Lymphoproliferative Disorders (F. Dammacco, ed.). Edi-Ermes, Milan, 1989, pp. 57-72. 3. Marone G., Casolaro V., Ayala F., Melillo G., Condorelli M.: Releasability in allergic disorders.
In: Respiratory Allergy. Clinical Immunology, vol. 2 (G. Melillo, P.S. Norman, G. Marone, eds.). B.C. Decker, Inc., Toronto, 1990, pp. 67-77. 4. Marone G., Casolaro V., Celestino D., Bonini S.: The role of genetic and environmental factors
in the control of basophil and mast cell releasability. In: Genetic and Environmental Factors in Clinical Allergy (D.G. Marsh, M.N. Blumenthal, eds.). University of Minnesota Press, Minneapolis, 1990, pp. 153-160. 5. Marone G., Casolaro V.: Basophil and mast cell releasability in allergic disorders. In: Cellular
Communications in Allergic Asthma (S.G.O. Johansson, ed.). AW Grafiska, Uppsala, 1990, pp. 45-53. 6. Columbo M., Casolaro V., Genovese A., Marone G.: Neurotransmitters and vasoactive mediator
release. In: Highlights in Allergy and Clinical Immunology (B. Wüthrich, ed.). Hans Huber Publishers, Seattle, Toronto, Bern, Göttingen, 1992, pp. 26-28. 7. Marone G., de Paulis A., Ciccarelli A., Casolaro V., Spadaro G., Cirillo R.: Antiinflammatory
effects of cyclosporin A. In: Progress in Allergy and Clinical Immunology, vol. 2 (T. Miyamoto, M. Okuda, eds.). Hogrefe & Huber Publishers, Seattle, Toronto, Bern, Göttingen, 1992, pp. 388-392. 8. Casolaro V., Stellato C., de Crescenzo G., Triggiani M., Marone G.: Mast cells, basophils and
their mediators. In: Asthma Treatment. A Multidisciplinary Approach (D. Olivieri, P. Barnes, S. Hurd, G. Folco, eds.). Plenum Publishing Co., New York, London, 1992, pp. 63-79. 9. Casolaro V., Spadaro G., Marone G.: Genetic studies of basophil releasability. In: The Genetics
of Asthma (D.G. Marsh, A. Lockhart, S.T. Holgate, eds.). Blackwell Science Ltd., Oxford, Boston, Melbourne, Berlin, Tokyo, Paris, 1992, pp. 291-308. 10. Marone G., Casolaro V., Spadaro G., Genovese A.: Bronchoalveolar lavage. In: Bronchial
Asthma: Mechanisms and Therapeutics (E.B. Weiss, M. Stein, eds.). Little, Brown and Company, Boston, Toronto, London, 1992, pp. 309-313. 11. Marone G., de Paulis A., Casolaro V., Ciccarelli A., Spadaro G., Patella V., Stellato C., Cirillo
R., Genovese A.: Are the anti-inflammatory properties of cyclosporin A useful in the treatment of chronic asthma? In: Respiratory Allergy: Advances in Clinical Immunology and Pulmonary Medicine (G. Melillo, P.M. O'Byrne, G. Marone, eds.). Excerpta Medica Medical Communications, Amsterdam, Oxford, New York, Tokyo, 1993, pp. 251-260. 12. Abdulkadir S.A., Casolaro V., Schwiebert L.S., Song Z., Ono S.J.: The major histocompatibility
complex genes and their transcriptional regulation. In: MHC Molecules: Expression, Assembly and Function (R. Chicz, R.G. Urban, eds.). R.G. Landes Co., Austin, 1996, pp. 9-35. 13. Georas S.N., Burke T.F., Chen R., Cumberland J.E., Casolaro V.: The molecular basis of IL-4
dysregulation in the atopic condition. In: Asthma and Allergic Diseases: Physiology, Immunopharmacology and Treatment (G. Marone, S.T. Holgate, A.B. Kay, K.F. Austen, L.M. Lichtenstein, eds.). Academic Press Ltd., London, Burlington, San Diego, 1998, pp. 171-192. 1. Columbo M., McKenzie-White J., Casolaro V., Warner J.A., Kagey-Sobotka A., Lichtenstein
L.M.: Platelet-activating factor (PAF) activates mediator release in human basophils. The Journal of Allergy and Clinical Immunology 1990; 85:215. 2. Columbo M., Casolaro V., Warner J.A., MacGlashan D.W., Jr., Kagey-Sobotka A., Lichtenstein
L.M.: The mechanism of human basophil mediator release by platelet-activating factor (PAF). The FASEB Journal 1990; 4:A2310. 3. Casolaro V., de Paulis A., de Crescenzo G., Patella V., Tatangelo F., Marone G.:
Immunopharmacological heterogeneity of human basophils and mast cells. Pharmacological Research 1990; 22(Suppl. 2):99. 4. Casolaro V., Patella V., Spadaro G., Björck L., Marone G.: IgE-mediated activation of human
FcεRI+ cells by protein L (PL). The Journal of Allergy and Clinical Immunology 1991; 87:242. 5. Stellato C., Tatangelo F., Casolaro V., Genovese A., Marone G.: Additive inhibition of mediator
release from human basophils by deflazacort and cyclosporin A. Schweizerische medizinische Wochenschrift 1991; 121 (Suppl. 40/I):51. 6. Patella V., Casolaro V., Marchesi E., Marone G.: Anti-inflammatory effect of loratadine on
human mast cells. Allergy 1992; 47:47. 7. Patella V., Casolaro V., Fratellanza G., Pettit G.R., Marone G.: Heterogeneity of the effects of
bryostatins on human basophils and mast cells. The Journal of Allergy and Clinical Immunology 1993; 91:257. 8. Casolaro V., Spadaro G., Patella V., Genovese A., Marone G.: Effect of in vivo administration
of cyclosporin A on human basophils. The Journal of Allergy and Clinical Immunology 1993; 91:329. 9. Genovese A., Stellato C., Casolaro V., Fratellanza G., Marone G.: Additive anti-inflammatory
effect of deflazacort and cyclosporin A or FK-506 on human basophils. The Journal of Allergy and Clinical Immunology 1993; 91:329. 10. Stellato C., Casolaro V., de Paulis A., Patella V., Tatangelo F., Marone G.: Heterogeneity of
mediator release induced by opioids from human mast cells. The Journal of Allergy and Clinical Immunology 1993; 91:364. 11. Marone G., Casolaro V., Marchesi E., Bianchi B., Patella V.: Inhibition of mediator release from
human mast cells by loratadine. The Journal of Allergy and Clinical Immunology 1994; 93:258. 12. Casolaro V., Georas S.N., Wang S.S., Song Z., Swendeman S.L., Sheffery M., Lichtenstein
L.M., Ono S.J.: Specificities and cell distribution of transcription factors binding to the interleukin 4 (IL-4) negative regulatory element (NRE). The Journal of Allergy and Clinical Immunology 1994; 93:285. 13. Georas S.N., Casolaro V., Wong S., Song Z., Ono S.: Characterization of nuclear factor binding
to the interleukin-4 (IL-4) promoter. The FASEB Journal 1994; 8:A778. 14. Casolaro V., Georas S.N., Wang S.S., Song Z., Lichtenstein L.M., Ono S.J.: Constitutive and
ubiquitous proteins bind to the human interleukin 4 gene promoter. Clinical Research 1994; 42:A308. 15. Casolaro V., Georas S.N., Chiu J.Y., Song Z., Thanos D., Lichtenstein L.M., Ono S.J.: NF-κB
as a mediator of differential gene expression in T helper cell subsets. The Journal of Allergy and Clinical Immunology 1996; 97:361. 16. Georas S., Cumberland J., Ono S., Casolaro V.: A novel repressor element in the interleukin 4
promoter. The Journal of Allergy and Clinical Immunology 1997; 99:S57. 17. Imani F., Rager K.J., Catipovic B., Casolaro V., Proud D., Langland J.O., Jacobs B.L., Marsh
D.G.: Viral infections of human B cells can induce the expression of IgE germline transcript. The Journal of Allergy and Clinical Immunology 1997; 99:S221. 18. Burke T.F., Cumberland J., Chen R., Casolaro V., Georas S.N.: NFAT/AP-1 interactions with
the human IL-4 promoter AP@ elements and description of a novel NFAT binding site. American Journal of Respiratory and Critical Care Medicine 1997; 155:A697. 19. Chen R., Cumberland J., Burke T., Freedman L., Casolaro V., Georas S.: A glucocorticoid
receptor binding site in the human interleukin-4 (IL-4) promoter. American Journal of Respiratory and Critical Care Medicine 1997; 155:A697. 20. Cumberland J., Burke T., Casolaro V., Chen R., Schindler U., Georas S.: Multiple STAT6
binding sites in the human interleukin-4 promoter. American Journal of Respiratory and Critical Care Medicine 1997; 155:A697. 21. Burke T.F., Cumberland J., Chen R., Casolaro V., Georas S.N.: A novel negative regulatory
element within the human IL-4 promoter. American Journal of Respiratory and Critical Care Medicine 1998; 157:A482. 22. Cumberland J., Burke T., Chen R., Casolaro V., Georas S.: Yin-Yang 1 inhibits transcription of
the human interleukin 4 gene. American Journal of Respiratory and Critical Care Medicine 1998; 157:A482. 23. Chen R., Cumberland J., Burke T., Casolaro V., Georas S.: Glucocorticoids directly inhibit
interleukin 4 transcription. American Journal of Respiratory and Critical Care Medicine 1998; 157:A869. 24. Kim J., Casolaro V., Proud D.: Rhinovirus (RV) induction of epithelial cytokines: Role of NF-
κB. The Journal of Allergy and Clinical Immunology 1999; 103:S116. 25. Nickel R., Barnes K.C., Sengler C., Casolaro V., Freidhoff L.R., Weber P., Naidu R., Caraballo
L., Plitt J., Schleimer R.P., The CSGA, Huang S.K., Beaty T.: Evidence for linkage of chemokine polymorphisms to asthma in populations of African descent. The Journal of Allergy and Clinical Immunology 1999; 103:S174. 26. Schroeder J.T., Cianferoni A., Casolaro V., Lichtenstein L.M.: Enhanced secretion of IL-4 by
human basophils following pretreatment with sodium salicylate and aspirin. The Journal of Allergy and Clinical Immunology 1999; 103:S192. 27. Matsukura S., Plitt J.R., Bickel C., Stellato C., Georas S., Casolaro V., Schleimer R.P.:
Molecular analysis of epithelial eotaxin gene expression. The Journal of Allergy and Clinical Immunology 1999; 103:S202. 28. Cianferoni A., Schroeder J.T., Vierucci A., Lichtenstein L.M., Georas S.N., Casolaro V.:
Differential effects of salicylates on IL-4 and IL-2 expression in human CD4+ T lymphocytes. The Journal of Allergy and Clinical Immunology 1999; 103:S240. 29. Valapour M., Cianferoni A., Cumberland J., Burke T., Seto E., Casolaro V., Georas S.: Histone
deacetylation inhibits interleukin-4 (IL-4) gene expression. American Journal of Respiratory and Critical Care Medicine 1999; 159:A908. 30. Cianferoni A., Schroeder J.T., Keen J.C., Schmidt J.W., Georas S.N., Casolaro V.: Dissociation
of the effects of salicylates on IL-4 gene expression and NFAT activation in human T cells. The Journal of Allergy and Clinical Immunology 2000; 105:S158-S159. 31. Florio G., Cianferoni A., Keen J.C., Schmidt J.W., Lakenan W.A., Georas S.N., Casolaro V.:
NF-κB-dependent transcription of the human IL-13 gene in activated T cells. The Journal of Allergy and Clinical Immunology 2000; 105:S278. 32. Barnes K.C., Nickel R., Mathias R.A., Freidhoff L.R., Casolaro V., Stockton M.L., Xue X.,
Ehrlich E., Naidu R.P., Levett P.N., Schou C., Huang S.-K., Togias A., Beaty T.H.: Interaction between loci on chromosomes 12q and 17q increases susceptibility to elevated total IgE in two distinct populations. The Journal of Allergy and Clinical Immunology 2000; 105:S370. 33. Barnes K.C., Mathias R.A., Freidhoff L.R., Nickel R., Casolaro V., Chilton F., Naidu R.P.,
Levett P.N., Schou C., Huang S.-K., Togias A., Beaty T.: Epistasis and environmental interactions with 12q21.31 increases susceptibility to allergic airway disease. International Archives of Allergy and Immunology 2000. 34. Guo J., Keen J., Casolaro V., Georas S.: Yin-Yang-1 (YY1): a critical regulator of IL-4 gene
expression. American Journal of Respiratory and Critical Care Medicine 2000. 35. Vonakis B.M., Sora R., Langdon J.M., Casolaro V., MacDonald S.M.: Inhibition of cytokine
gene transcription by the human recombinant histamine releasing factor (HrHRF) in human T lymphocytes. The Journal of Allergy and Clinical Immunology 2001; 107:S60. 36. Guo J., Christodoulopoulos P., Keen J., Casolaro V., Hamid Q., Georas S.: YY1, a novel
regulator of IL-4 gene expression. The Journal of Allergy and Clinical Immunology 2001; 107:S68. 37. Zambelli-Weiner A., Casolaro V., Mathias R.A., Stockton M.L., Nutman T.B., Barnes K.C.:
Cross-reactivity of T cell responses to major allergens of cockroach and antigens from extracellular parasites in individuals with cockroach sensitization. The Journal of Allergy and Clinical Immunology 2001; 107:S86. 38. Keen J.C., Natarajan S., Burke T., Guo J., Cianferoni A., Schmidt J., Casolaro V., Wills-Karp
M., Georas S.N.: Distinct signal requirements for IL-4 and IL-13 expression. The Journal of Allergy and Clinical Immunology 2001; 107:S148. 39. Schroeder J.T., Miura K., Cianferoni A., Kim H.H., Roche E., Sin A., Casolaro V.: Nuclear
factor of activated T cell (NFAT) expression in human basophils: evidence for NFAT2 involvement in IgE-mediated IL-4 generation. The Journal of Allergy and Clinical Immunology 2001; 107:S307. 40. Leng S.X., Yang H., Koenig K., Casolaro V., Walston J.: Immunologic correlates of the
geriatric syndrome of frailty. Journal of the American Geriatrics Society 2001; 49:P241. 41. Guo J., Keen J., Natarajan S., Casolaro V., Georas S.: Regulation of Th2 cytokine gene
expression by c-Jun and JNK. American Journal of Respiratory and Critical Care Medicine 2001. 42. Haliassos N., Casolaro V., Holt K., Ray A., Georas S., Guo J.: GATA-3 activates the IL-13 gene
promoter in T cells. The Journal of Allergy and Clinical Immunology 2002; 109:S401. 43. Rubenfeld J., Guo J., Cummings R., Natarajan V., Casolaro V., Georas S.: Lysophosphatidic
acid (LPA) amplifies IL-13 expression in submaximally stimulated T cells. American Journal of Respiratory and Critical Care Medicine 2002. 44. Zambelli-Weiner A., Farkas D.H., Chan V., Mathias R.A., Casolaro V., Barnes K.C.: The
transcriptional factor LBP-1c/CP2/LSF gene in chromosome 12q13 is not associated with asthma in two independent populations. American Journal of Human Genetics 2002; 71:356. 45. Kurnat R.J., Georas S.N., Curry S., Meng X., Huang S., Cunningham J.M., Stellato C., Casolaro
V.: The transcription factor CP2 is required for IL-4 gene activation in effector Th cells. The
Journal of Allergy and Clinical Immunology 2003.
46. Saatian B., Yu X.Y., Lane A.P., Casolaro V., Spannhake E.W.: Concordance of expression of
genes for cell surface immune molecules between nasal epithelial cells from nasal brushing and cells grown in culture at the air liquid interface. American Journal of Respiratory and Critical Care Medicine 2003. 47. Lane A.P., Saatian B., Yu X.Y., Casolaro V., Spannhake E.W.: Expression of cell surface
immune molecule genes by human middle meatal epithelial cells in culture. 2003 Combined Otolaryngological Spring Meeting of the American Rhinologic Society. 48. Georas S., Yamagata T., Ray A., Casolaro V., Guo J.: GATA-3 is inducibly acetylated in T cells
and activates the IL-13 promoter. The FASEB Journal 2003; 17:C102. 49. Guo J., Casolaro V., Kurnat R., Shi Y., Georas S.: Yin-Yang-1 regulates allergic immune
responses and Th cytokine gene expression. The FASEB Journal 2003; 17:C102. 50. Hellquist A.S., De Fanis U., Holland T.S.L., Gupta V., Kurnat R.J., Cianferoni A., Casolaro V.:
Activation of nuclear factor of activated T cells (NFAT) molecular species by aspirin (acetylsalicylic acid: ASA) in human T cells. The Journal of Allergy and Clinical Immunology 2004; 113:S252. 51. Guo J., Shi Y., Casolaro V., Georas S.: Allergic airway inflammation is blunted in YY1
deficient mice. American Journal of Respiratory and Critical Care Medicine 2004. 52. De Fanis U., Bova M., Lee W., Kurnat R.J., Casolaro V.: Polarized expression of GATA3 is not
sufficient for CRTH2 and IL-4 gene activation in differentiated human Th2 clones. The Journal of Allergy and Clinical Immunology 2005; 115:S135. 53. Mori F., Hellquist A.S., Holland T.S.L., Cianferoni A., De Fanis U., Casolaro V.: Enhancement
of NFAT activation and function by aspirin in T cells. Pediatric Research 2005; 58:398. 54. Chian C.F., Gao P.S., De Fanis U., Casolaro V., Adkinson N.F., Jr., Huang S.K.: Phenotypic
assessment of a functional sequence variant of the gene encoding human chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2). The Journal of Allergy and Clinical Immunology 2006; submitted. 55. De Fanis U., Mori F., Limb S.L., Hamilton R.G., Adkinson N.F., Jr., Casolaro V.: Expression of
polarized T-cell surface markers in respiratory allergy. The Journal of Allergy and Clinical Immunology 2006; in press. 56. Kurnat R.J., De Fanis U., Lee W., Georas S.N., Guo J., Casolaro V.: Differential expression of
NF-κB molecular species in Th1 and Th2 cells. The Journal of Allergy and Clinical Immunology 2006; in press. 1. Mori F., De Fanis U., Kurnat R.J., Lee W., Casolaro V.: Aspirin exerts opposite regulation of
CD154 and cytokine gene expression in human Th1 and Th2 cells. The Journal of Allergy and Clinical Immunology 2006; in press.

Source: http://icm.jhu.edu/affiliated-faculty/CVs/casolaro_CV.pdf