Director, Dow Diagnostic Research and Reference Laboratories (DDRRL), Associate Professor & Head Pathology Department, Dow International Medical College Dow University of Health Sciences, Karachi, Pakistan. Telephone: Off: 021-4946447, Res: 021-4922594, 4914154, Cell: 0300-8276387, Fax: 021-2257981. email:Nationality: Canada & Pakistan
ACADEMIC QUALIFICATION Dow Medical College, Karachi, Pakistan.
Basic Medical Sciences Institute, Jinnah Postgraduate
Jinnah Post Graduate Medical Centre, Pakistan
WORK HISTORY Focal Person, Provincial Reference Laboratory for Tuberculosis OJHA
Director Dow Diagnostic Reference & Research Laboratory, DUHS
Associate Professor Pathology, Dow International Medical College, DUHS 2007-2008
Assistant Professor of Pathology (Microbiology), Sindh Medical College 2003-2006
Assistant Professor of Pathology (Microbiology), Liaqat University 2002.2002
Project Director, Seniors Health Volunteer Program (GSK, Canada)
President, Association of International Physicians and Surgeons of Ontario 1999-2002
Assistant Professor of Microbiology, Sindh Medical College 1992-1997
House Officer Pediatrics, Internal Medicine and Surgery
RESEARCH PROJECTS : Principal Investigator, Male having sex with males project for the prevention of STIs
including HIV in Karachi, Hyderabad, Sukkur
Principal Investigator, Canada-Pakistan HIV/AIDS Surveillance Project 2004-2005
Pilot Study of Karachi. (Mapping and Integrated Biological and Behavioral Surveillance)
Efficacy of Matrix Gel in treatment of Chronic Osteoarthritis
Comparison of Typhidot and Tubex in the diagnosis of Typhoid Fever
Safety and efficacy of Clomid, a multi center trial
Co-Investigator, genetic profile of malignant tumors and role of new drugs Jan-Dec 2008
JOB DESCRIPTION Teaching 3rd and 4th year students of Medical School and Postgraduates students of M.
Phil, Ph D., Masters of Dental Surgery (MDS), DTCD (Diploma in Tuberculosis and Chest
Diseases) the subject of Microbiology which includes Bacteriology, Virology, Mycology and
Teaching of Medical Laboratory Technologists,
Research and clinical trials: Treatment of Breast Ca (HER-2 +) with monoclonal antibodies,
Safety and efficacy of silicone gel in chronic OA, compliance of HAART in HIV/AIDS,
Hepatitis B and C, Tuberculosis, Rubella, community and hospital infections, infection
control, investigation of outbreaks of various infections in community and hospitals. OTHER EXPERIENCE/TRAININGS
Microbiology at District Headquarter Hospitals
ELISA and Western Blot for Lab Diagnosis AIDS
PCR in Laboratory diagnosis and monitoring of patients
WHO/NIH Workshop on Quality Assurance in
First National Workshop/certificate course on
Immunology, Immunodiagnosis and Flowcytometry
Workshop on Viral Diagnostics, Department of
Care of small animals in Laboratory research
Infection Control Issues in Developing World, IDSP
National Workshop on Mapping Techniques for
Workshop on Integrated Biological & Behavioral
Surveillance by Canada Pakistan HIV/AIDS
Qualitative Research Methods and Evaluation
by the University of Alabama at Birmingham
School of Public Health, Fogarty International Center
US-Pakistan International Workshop”Molecular Biology
Molecular Biology Conventional & Real Time PCR
Molecular Biology, DNA Extraction & Isolation
Taking Forward ARV Treatment Program in Pakistan
Infection Control-Implementation of WHO Hand Hygiene Guidelines
Clinical Trials-GCP, GMP and GLP in Pakistan
ORGANIZER
Training of Master Trainers for Prevention and Control of HIV/AIDS
Developing Strategies for Control of HIV/AIDS (NAZ Project)
13th Annual Conference, Pakistan Association of Pathologists
First Series of International Seminars (I.C.S.P.)
First Immunology and Infectious Disease research
Lab-(IIRDL) Annual Symposium of Microbiology
National Workshop on Immunology Immodiagnosis
First Annual Conference, Pakistan Society for
Second International Seminars and Workshops
Second Annual Conference, Pakistan Society for
Third Series of International Seminars (I.C.S.P.)
ADDITIONAL ASSIGNMENTS Editor:
Pakistan Society for Microbiology Souvenir
Infection Control Society, Pakistan Souvenir
Annals of Abbasi Shaheed Hospital & KMDC (Member Board)
Editor-Inchief
Jehan-e-Sehat Urdu Health Magazine (Monthly)
Medical Journal:
Advisor to Annals Abbasi Shaheed Hospital and Karachi Medical & Dental Council, Karachi
IFIC Newsletter; Member International editorial Advisory Board,
International Federation of Infection Control
Associate Editor: Journal of Dow University of Health Sciences (JDUHS) 2007-2008
Member Editorial Board: JPMA HIV/AIDS Supplement, Tuberculosis
Ethical Review Board, Dow University of Health Sciences 2007-8
Ethical Review Board, Bridge Health Research
Ehical Review Committee, Abbasi Shaheed Hospital 2007-8
Memon Medical Institute Advisory Committee
ADDITIONAL EXPERIENCE
Facilitator/Trainer various Workshops and Seminars on AIDS and HIV Infections
(AIDS Control Program Sindh, Alliance for AIDS Prevention Toronto)
Focal Person, Provincial Reference Laboratory, National TB Control Program
Invited lecturer to College of Medical Technology, JPMC
Teaching Advisor, Immunology & Infectious Diseases Research Lab,
Department of Microbiology, University of Karachi. MEMBERSHIP OF PROFESSIONAL ORGANIZATIONS NAME OF ORGANIZATION POSITION
International Society of Infectious Diseases (ISID)
Asia Pacific Society of Medical Virologists
Infection Control Society Pakistan (I.C.S.P.)
Pakistan Association of Pathologist (PAP)
Pakistan Medical and Dental Council (PMDC) Regulatory
SELECTED BIBLIOGRAPHY/PUBLICATIONS
1. Khanani, M.R., Hafiz,A., Rab,S.M. and Rasheed, S. Human Immunodeficiency
Virus Associated Disorders in Pakistan. AIDS Research and Human Retroviruses. (USA) 1988 4(2) : 149- 154.)
2. Mujeeb, S.A., Khanani, M.R., Khursheed, T. and Siddqui, A. Prevalence of HIV
infection among blood donors. JPMA 1991; 41: 10.
3. Khanani, M.R. Acquired Immunodificiency Syndrome (AIDS). Sereopidmiology and
4. Khanani, M.R., Hafiz, A.,Rab, S.M and Rasheed, S. AIDS and HIV associated
disorders in Karachi. JPMA (1990)., 40: 82-85.
Khanani M.R., and Hafiz, A. Diagnosis and management of AIDS. Medical pectrum,1985. (Review)
6, Khanani, M.R. Mugheesuddin, A. Suleman, N. And Hussain, Z. Viral Hepatitis;
An every day problem. National Health, 1988.
7, Khanani, M.R., Sandila, T., Hayat A., Shaikh, M. and perveen, N. Penicillinas
producing Neisseria Gonorrhoeae (PPNG) in Pakistan, 13th Cong. Western Pacific Assoc. Antimicro. Chemo. Ther. Agents,Phil ipines, 1990.
8, Khanani, M.R., Memon, S, Memon, R.A., Ali, M. and Guaba, P.K. Seasonal
9. Khanani, M.R., Memon, A.R., Shaikh, R.B., Ali, G., Shaikh, M. Sandila, T., Hussain,
Z. and Parveen, N. B-Lactamase producing neisseria gonogrrhea strains in Karachi. J.P.M.A. 44:70, 1994.
10. Mujeeb SA., Khanani MR. and Ahmed MU. Laboratory Diagnosis of HIV/AIDS.
Infection (Ediorial) Annals, Abbasi Shaheed Hospital and Karachi Medical & Dental Col ege, Karachi, 1995.
11. Shaikh RB, Hafiz A., Khanani MR and Rab SM. Efficacy of bacterial culture of bone
marrow versus peripheral blood in laboratory diagnosis of typhoid fever. Pakistan Journal of Pathology. 1994: 5(2); 27-28,.
Ali G., Memon U., Khanani MR., Naz F. and Kazmi B. Value of Exhumation Specialist PJMS:1995 11(3).
13. Ali G., Khanani MR., Memon U., Memon A., Sanaullah S. and Seema N. Pattern of
Injuries in Road, Traffic Accidents (RTA) in Karachi City: Specialist PJMS: 1995 11(2).
14. Ali G., Memon A., Memon U., Khanani MR., Ayaz K. and Jabeen M. Factorial
Analysis of Narcotic drug abuse in Karachi City. Specialist PJMS: 1994 10(4).
15. Khanani MR., Naqvi HN. and Memon R. Problems with Methicil in resistant
staphylococcus aureus in a major teaching hospital in Karachi, Pakistan 3rd International Conference of the Hospital Infection Society, London.
16. Khanani MR., Naqvi HN., and Billoo AG. Bengal strain of V.cholera '0139' in Karachi
Pakistan 3rd International Conference of the Hospital Infection Society, London.
17. Ali S., Khanani MR., Tariq WZ. and Shah SA. Understanding the HIV/AIDS context
in Pakistan. Venereology (Australia) 1995 8(3): pp152-54.
Ali G., Memon A., Memon U., Ahmed G and Khanani MR. Pattern of fatal Injuries in Railway Accidents: Specialist PJMS: 1994:11(1):47-49
Hussain S., Ali G., Khanani MR., Makhdoom PA., and Sanaullah. Pre hospital measures for snake bites in Sindh. Specialist PJMA 1995: 12(1); 23-26.
Nawab H., Ehsanullah S., Haider W and Khanani R Visceral Leishmaniasis in Karachi. Specialist PJMS: 1996:12(3):217-220
Mujeeb SA, Jamal Q, Khanani R., Iqbal N., and Keher S. Prevalence of hepatitis B surface antigen and HCV antibodies in hepatocellular carcinoma cases in Karachi, Pakistan. Tropical Doctor, (UK) 1997 ; 27
Nawab H., Hafiz A., Ehsanullah S., Haider W and Khanani R Cutaneous Leishmaniasis in Karachi. Specialist PJMS: 1997:13(4):383-388
23. Mujeeb SA, Khanani MR., Shiekh MA: Prevalence of hepatitis C Virus infection
among B-thalassaemia major patient. Tropical Doctor, ( UK) 1997: 27(1).
Ali G., Khanani MR., Shaikh MA., Memon AR., and Naqvi HN. Knowledge and attitudes of Medical Students to people with HIV and AIDS: JCPSP, 1996; 6(1); 58-61.
Rehebilitation of grade III PEM in an outpatient Clinic. JPMA, 1995; 45(12); 312-314.
Ahmed M., Khanani MR., and Hafiz A. AIDS Diagnosis and Management. JCPSP, 1996; 6(1); 78-82.
Nawab H., Khanani MR., Shaikh M., Ehsanullah S., and Haider W. The Immune status of adult females in Karachi to Rubel a virus infection. Specialist, PJMS, 1997; 13(2): 1-5.
Jamal A., Khanani MR., Bil oo G., Asghar A. and Jafri Z. Rickets in a slum of Karachi. Specialist, Pak. Med. Sci. 1996: 12 (3):247-250
S.A. Mujeeb, Y. Khatri and R. Khanani, Frequency of parenteral exposure and seroprevalence of HBV, HCV, and HIV among operation room personnel. Journal of Hospital Infection , UK,(1998) 38, 133-137
Sub-national response in HIV/AIDS a case study in AIDS prevention and control from Sindh province, Pakistan. AA Hyder, OA Khan, Mr, SA Shah, MA Memon, MR Khanani and S Ali: January 1999, Pages 39-43
S. Luby, R. Khanani, Zia M., Vellani Z., Ali M., Qureshi AH., Khan AJ., Mujeeb SA., Shah SA., and Fisher-Hoch S. Evaluation of blood bank practices in Karachi, Pakistan and the Government’s response. Health Policy and Planning, UK, (2000),
Antiretroviral drugs obtained without prescription for treatment of HIV/AIDS in Pakistan: S.A. shah, A. Altaf, R. Khanani and S.H. Vermund. JCPSP 2005, 15 (6): 378- 380
33. Mohammad A. Rai., Muhammad Nausherwan Khan, Saeed Khan, Rafiq Khanani
and Syed H. Ali. Pakistan/India open borders….to HIV? AIDS (2006)
34. Khan, S., M. N. Khan, M. A. Rai, R. Khanani, S. H. Ali (2006). Prevalence of HIV-1
subtype A in a high- risk community of Pakistan. International AIDS Conference, Toronto, Canada (2006)
35. Rai, M. A., V. R. Nerurkar, S. Khan, M. R. Khanani, R. Yanagihara, S. H. Ali (2007).
Evidence for a “Founder Effect” among HIV-1-infected injection drug users in Karachi, Pakistan. Health Sciences Research Assembly, Aga Khan University, Karachi, Pakistan.
36. Khan, S., N. Khan, R. Khanani, S. Ali (2005). Molecular epidemiology of HIV in
Pakistan. Health Sciences Research Assembly, Aga Khan University, Karachi, Pakistan.
Vermund SH, White H, Shah SA, Altaf A, Kristensen S, Khanani R, Mujeeb AS: HIV/
AIDS in Pakistan: Has the explosion begun? J Pak Med Assn 2006; 56 (suppl 1): S1-
38. Khan S., Rai MA, Khanani MR, Khan MN and Ali SH. HIV-1 subtype A
infection in a community of intravenous drug users in Pakistan. BMC
39. Rai MA, Khanani MR, Warraich HJ, Hayat A, and Ali SH, Crimean Congo
Haemorrhagic Fever in Pakistan, Journal of Medical Virology, 2008
Rajabali A, Khan S, Warraich HJ, Khanani MR, Ali SH. HIV and homosexuality in
Pakistan. The Lancet Iinfections Vol 8, 2008
Tang JW, Khanani MR, Zubairi A , Lam WY, Lai F, Hashmi K, Hussain A, Jamal S,
Chan PK. A wide spectrum of dengue IgM and PCR positivity post-onset of il ness
found in a large dengue 3 outbreak in Pakistan, Journal of Medical Virology. (2008)
Baqi S , Damani N, Shah SA, Khanani R. Infection Control at a Government Hospital
in Pakistan. Int J Infect Control 2009, 5 (1);.004.09
Rajabali A, Moin O, Ansari AS, Khanani MR and Ali SH. Communicable disease
among displaced Afghans: refugee without shelter. Nature Reviews Microbiology
Hussain M, Khanani MR , Jabeen N, Shoaib SS & Mirza T.
"Protein homology modeling and structure-function relationship of 2009 swine
influenza virus hemagglutinin (HA1): more human than swine.", Biologia, Bratislava
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Nutritionalsupplementation inDown syndrome:theoreticalconsiderations andcurrent statusCornelius Ani* MBBS MSc DCH, Research Fellow;Sally Grantham-McGregor MBBS MD, Professor of ChildHealth and Nutrition, Centre for International Child Health;David Muller PhD, Reader in Biochemistry, BiochemistryUnit, Institute of Child Health, University College London,London, UK. *Correspondence to first autho