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Curriculum Vitae
Dr. Raid J. Abdel-Jalil
On Leave at:
Present address:
Chemistry Department
http://www.squ.edu.om/tabid/7516/language/en-US/Default.aspx Summary:
Associate professor in organic chemistry, 33 scientific publications, a post-doc in the department of pharmacology at UCLA-USA and a Ph.D. from University of Tuebingen-Germany Education


Postdoctoral Fellow University of California Los Angeles (UCLA)
2000-2001
Department of Pharmacology/ School of Medicine
Postdoctoral Fellow, Mentor: Prof. Tatsushi Toyokuni Development of F-18 labeling agents for targeting biomolecules: Synthesis and applications to the labeling of ODNs and antibody fragments Ph.D.
University of Tuebingen, Tuebingen (Germany),
Dissertation Title: "Anhydropyranoses as Chirons for Regio- and Stereoselective Synthesis of Chiral Heterocyclic Systems, (4→4)-Di(2,3-anhydropentopyranosides), 4-(4-Substituted-1-piperazinyl)- 2,3-anhydropentopyranosides and Cyclopentane Derivatives." DAAD (Deutscher Akademischer Austausch Dienst-Germany) Fellowship (1996-1999)
M.Sc.
University of Jordan, Amman (Jordan)
Thesis Title: "Synthesis and Bioassay of Some 5-Flouro-6-(1- Prof. Dr. S. Sabri; Co-advisor: Prof. Dr. M. El-Abadelah Fellowship from Hikma Pharmaceuticals Company (1992-1995).

B.Sc.

University of Jordan, Amman (Jordan),
Positions and Experience

1. Assistant Professor, Chemistry Department, College of Science, Sultan Qaboos University,
2. Consulting Visitor, Chemistry Department, College of Science, Sultan Qaboos University,
3. Chairman, Chemistry Department, Faculty of Science, Hashemite University: 2007/2008.
4. Vice Dean, Faculty of Science, Hashemite University: 2006/2007.
5. Chairman, Chemistry Department, Faculty of Science, Hashemite University: 2005/2006.
6. Associate Professor (Organic Chemistry), Chemistry Department, Faculty of Science, Hashemite
7. Assistant Professor (Organic Chemistry), Chemistry Department, Faculty of Science, Hashemite
8. Post-doc Fellow: Department of Pharmacology, School of Medicine, University of California at
Research interest

1. Asymmetric Synthesis
2. Heterocyclic synthesis
3. Microwave synthesis
4. Developing of new hpoxia PET tracers

PUBLICATIONS LIST:

1. M. M. El-Abadelah, S. S. Sabri, M. H. Abu Zarga, R. J. Abdel-Jalil, “Substituted Benzimidazoles.
Synthesis and Properties of some 2-Aryl-5-fluoro-6-(4-methyl-1-piperazinyl)-1H-benzimidazoles”
Heterocycles, 41, 2713 (1995).
2. R. J. Abdel-Jalil, R. A. Al-Qawasmeh, W. Voelter “(4→4)-Di(2,3-anhydropentopyranosides), a
Novel Class of Potential Enzyme Inhibitors” Tetrahedron Lett. 39, 6155 (1998).
3. R. J. Abdel-Jalil, R. A. Al-Qawasmeh, Y. Al-Abed, W. Voelter“A Stereospecific Synthesis of
Tetra-Substituted Chiral Piperazines” Tetrahedron Lett. 39, 7703 (1998).
4. R. A. Al-Qawasmeh, R. J. Abdel-Jalil, T. H. Al-Tel, R. Thürmer, W. Voelter, “A Useful
Regioselective Approach to Episulfides via cis-oriented Anhydro Triflate Sugars”, Tetrahedron
Lett
. 39, 8257 (1998).
5. R. A. Al-Qawasmeh, T. H. Al-Tel, R. J. Abdel-Jalil, R. Thürmer, W. Voelter*, “Anhydro Sugars
to Enantiomerically pure Building Blocks: Efficient syntheses of γ-Lactones and Furanoids”,
Polish J. Chem. 73, 71-75 (1999).
6. W. Voelter, R. Thürmer, R. A. Al-Qawasmeh, T. H. Al-Tel, R. J. Abdel-Jalil, Y. Al-Abed,
“Epoxy Pyranoses, Chiral Synthons for Versatile Regio- and Stereocontrolled Functionalizations”,
Polish J. Chem. 73, 55-69 (1999).
7. R. A. Al-Qawasmeh, T. H. Al-Tel, R. J. Abdel-Jalil, W. Voelter, “Carbohydrates to Heterocycles:
A new Strategy for the Synthesis of Enantiomerically Pure Pyridazines and Oxazines Derived from
Epoxypyranoside Scaffolds” Chem Letters, 541 (1999)
8. Khalid M. Khan, Zafar S. Saify, Zeeshan, Abdullah Khan, Mansoor Ahmed, Muhammed Saeed, Raid J. Abdel-Jalil, Gerald Grübler, Wolfgang Voelter, “Syntheses of Selected Quaternary
Phenacylbromopyridinium Compounds and their Biological Evaluation”, Z. Naturforsch. 54b,
1210-1218. ( 1999).
9. R. J. Abdel-Jalil, Raed Al-qauasmeh, Mustafa El-Abadelah, Salim Sabri and Wolfgang Voelter,
“Synthesis and Properties of 6-Flouro-7-(1-Methyl-4-piperazinyl)quionoxalines”, J. Heterocyl.
Chem
., 37, 1273 (2000).
10. R. J. Abdel-Jalil, Muhammed Saeed and Wolfgang Voelter, “Synthesis and properties of some
substituted Anhydro Sugars”, Z. Naturforsch., 55b, 661-666 (2000).
11. Mustafa M. El-Abadelah, Salim S. Sabri, Monther Khanfar, Wolfgang Voelter, Raid J. Abdel-
Jalil, Calcia Maichele-Mossmer and Yousef Al-Abed, “Syntehsis and Properties of α-Thiagra. A
Substituted 5-(2-Thienyl)Pyrazolo[4,3-d]Pyrimidin-7-one Bioisotere of Viagra”, Heterocycles, 35
2643-2652 (2000).
12. Muhammed Saeed, R. J. Abdel-Jalil, Wolfgang Voelter, Mustafa El-Abadelah, " An expeditious
synthesis of optically pure 1,4,5,6-tetrahydro-as-triazines, fused to the carbohydrate skeleton”,
Chem. Letters, 7, 660-661 (2001).
13. R. J. Abdel-Jalil, Muhammed Saeed and Wolfgang Voelter, " An Expeditious Approach To Tri
Substituted Chiral Thiazolines”, Tetrahedron Letters, 42, 2435-2437 (2001).
14. M. Saeed, M. Abbas, R. J. Abdel-Jalil, M. Zahid and W. Voelter, “ A convenient Method for the
Synthesis of Cylic Trithiocarbonates on Carbohydrate Scaffolds”, Tetrahedron Letters, 44, 315-
317 (2003).
15. R. J. Abdel-Jalil, W. Voelter and M. Saeed, " A novel Method for the Synthesis of 4(3H)-
Quinazolinones”, Tetrahedron Letters, 45, 3475-3476 (2004).
16. S. T. Shah, R. J. Abdel-Jalil, K. Khan, A. Heinrich, M. Richter and W. Voelter, “ Regioselective
Conversion of Anhydro Sugars into Halohydrins and X-ray study”, Z. Naturforsch., 59b, 337-340
(2004).
17. R. J. Abdel-Jalil, and Wolfgang Voelter, “ Synthesis of New 2-Fuoro-6-(4-substituted-1-
piperazinyl)-1H-Benzimidazoles of Potential Biological Interest”. J. Heterocylic Chem., 42, 1-5
(2005).
18. R. J. Abdel-Jalil, M. Khanfar, K. Abu-Safieh, S. Al-Gharabli, M. El-Abadelah and W. Voelter,
“Efficient One-Pot Synthesis of Pyrazolopyrimidines, Intermediates for Potential
Phosphodiesterase Inhibitors”, Monatshefte Chem., 136(4), 619-624 (2005).
19. Z. S. Saify, N. Mushtaq, K. Khan, S. Perveen, S. Tasadaque, R. J. Abdel-Jalil, M. Fecker and W.
Voelter, “ Synthesis and Pharmacological Activity of 4-(4-Chlorophenyl)-4-Hydroxypiperidine
Derivatives”, Chem. Pharm. Bull., 53, 64-66 (2005).
20. K. Khan, S. G. H. Maharvi, S. Perveen, M. T. Khan, S., R. J. Abdel-Jalil, S. Tasadaque, A. Shah,
M. Fecker, M. I. Choudhary, A. Ur-Rahman and W. Voelter,” Synthesis of Methyl Ether Analogues of Sildenafil (Viagra®) Possessing Tyrosine Inhibitory Potential” Chemistry & Biodiversity, 2, 470-476 (2005). 21. R. J. Abdel-Jalil, R. Stoll and Wolfgang Voleter, “ Microwave-Assisted Synthesis of 1-Aryl-3-
acetyl-1,4,5,6-Tetrahydrobenzimidazo [2,3,d]- [1,2,4]Triazines: The First Example of a Novel
Ring System”, Tetrahedron Letters, 46, 1725 (2005).
22. R. J. Abdel-Jalil, S. T. Shah, K. Khan and W. Voelter, “ Anovel Route Towards the Synthesis of
Stereospecific N-Substituted Chiral Morpholines”, Letters Org. Chem., 2(4), 306-308 (2005).
23. R. J. Abdel-Jalil, S. T. Shah, K. Khan and W. Voelter, “ Stereospecific Synthesis of Chiral
Tetrahydroquinoxaline, 2,3-dihydro-benzo[1,4]dioxin and 2,3-dihydro-naphtho[2,3-b][1,4]-dioxin
Derivatives. ”, Letters Org. Chem., 2(3), 238-241 (2005).
24. R. J. Abdel-Jalil, M. Khanfar, S. Al-Gharabli, M. El-Abadelah and W. Voelter, “High
Throughput Synthesis of Pyrazolopyrimidines via Copper-catalysed Cyclization, and X-Ray
Study”, Heterocycles 65(8), 1821-1827 (2005).
25. R. J. Abdel-Jalil, Hani M. Aldoqum, Mikdad T. Ayoub, and Wolfgang Voelter, “Synthesis and
Antitumor Activity of 2-Aryl-7-fluoro- 6-(4-methyl-1-piperazinyl)-4(3H)-Quinazolinones”,
Heterocycles, 65(9), 2061-2070 (2005).
26. R. J. Abdel-Jalil, Michael Übele, Walter Ehrlichmann, Wolfgang Voelter and H.-Jürgen
Machulla, "1-[18F]Fluoroethyleneglycol-2-Nitroimidazoles, a New class of Potential Hypoxia
PET Markers", J. Radioanalytical and Nuclear Chemistry, 267, 557-560 (2006).
27. M. Z. Al-Noaimi, R. J. Abdel-Jalil, S. F. Haddad, R. H. Al-Far and R. J. Crutchy, “ Ruthenium(II)
Complex of the Novel Azoimine Ligand, α-acetyl-α-Phenylazochlorophenylazomethane”
Inorganica Chimica Acta, 359, 2395-2399 (2006).
28. M. Z. Al-Noaimi, R. J. Abdel-Jalil, M. El-Abadelah, S. F. Haddad, and W. Voelter, “ Metal-
Assisted Oxidation Cyclization of Arylamidrazones I. Synthesis of 3-Acetyl-1,4-Dihydro-1-
Phenyl-1,2,4-Benzotriazine”. Monatshefte Chem., Monatshefte Chem., 137(6), 745-750 (2006).
29. R. J. Abdel-Jalil, Wolfgang Voelter, Calcia Maichele-Mossmer, Younes Baqi and H.-Jürgen
Machulla, "Crystal Structure of 2-(3-acetyl-1-(4-bromophenyl)-5-[(R)-4-chlorophenyl]-1,2,4-
triazolo-4-yl)-deoxy-1,3,4,6-tetraacetyl-β-D-glucose” Z. Kristallogr. NCS, 221 (2006).
30. R. J. Abdel-Jalil, Wolfgang Voelter, Calcia Maichele-Mossmer, Dirk Loefler and H.-Jürgen
Machulla, " Crystal structure of N,N,N-tris[2-(2-nitro-1H-imidazol-1-yl)ethyl]amine’,
Z. Kristallogr. NCS, 223, 505-506 (2008).
31. Khaled H. Abu Elteen, Raid J. Abdel-Jalil, Mawieh A. Hamad, Samer I. Al-Gharabli, Mohamad
Ghaleb, Khalid M. Khan, and Wolfgang Voelter, " Fungicidal Effects of Some Derivatives of 2-
Ferrocenyl Benzimidazoles: A Possible Template for Antifungal Drug Design" , Journal of
Medical Sciences
, accepted (2008).
32. R. J. Abdel-Jalil, M. Aqarbeh, D. Loeffler, B. Shen, S. Abo Orabi, W. Voelter and H.-Jürgen
Machulla, " Synthesis and radiolabeling of new N-[(4-[18F]Fluorobenzylidene) aminooxy) alkyl]-
2-nitroimidazoles as possible hypoxia imaging pharmaceuticals", J. Radioanalytical and Nuclear
Chemistry
, 283, 239-243, (2010).
33. R. J. Abdel-Jalil, E. Q. El Momani , M. Hamad, W. Voelter, M. S. Mubarak, B. H. Smith and D.
G. Peters,” Synthesis, antitumor activity, and electrochemical behavior of some piperazinyl
amidrazones”, Monatshefte fuer Chemie, 141, 251-258 (2010).
34. P. Dolashka-Angelova, R. J. Abdel-Jalil, R. A. Al-Qawasme, N. Stambolieva and Wolfgang
Voelter, ” Synthesis and inhibition properties of a series of pyranose derivatives towards a
Zn-metalloproteinase from Saccharomonospora canescens”, Carbohydrate Res.-accepted (2010).

Patent:
Abdel-Jalil, Raid; Al-Abed, Yousef; El-Abadelah, Mustafa M.; Khanfar, Monther; Sabri, Salim
S.; Voelter, Wolfgang. Pyrazolopyrimidinone Derivatives Conjugated to Thiophene Moieties or
Benzo [fused] 5-membered heterocycles for Erectile Dysfunction. PCT Int. Appl. (2001), 37 pp.
WO 0103644 A2 20010118 AN 2001:50436.


PRESENTATIONS at International Scientific Conferences:
1. Raid J. Abdel-Jalil, Ehab Q. Al-Momani, Lubna Tahtamooni, H.-J. Machulla and Wolfgang
Voelter, “Synthesis and in vitro Antitumor Activity of Some 7-Fluoro-6-(4-methyl-1-piperazinyl)-
2-(thiosubstituted)-4(3H)-quinazolinones”, 9th International Conference of Heteroatom
Chemistry
, Oviedo, Spain, July 2009.
2. Raid J. Abdel-Jalil, Eman mahmoud, and wolfgang Voelter, “Synthesis and antitumor activities
of some 3-(4-substituted-1-piperzinyl)-4-methylbenzo[g]cinnolines”, The Leading European
Event for Drug Discovery (MipTec-2007)U, Basel, Switzerland, 7-10 May, 2007.

3. Raid J. Abdel-Jalil, Hani Aldoqum, Mikdad A. Arif and wolfgang Voelter, “Synthesis and
antitumor activity of 7-fluoro-6-(4-methyl-1-piperazinyl)-2-aryl-4(3H)-quinazolinones”, Sixth
Tetrahedron Symposium, Challenges in Organic Chemistry
, Purdue, France 29-1 July, 2005.
4. Raid J. Abdel-Jalil and Wolfgang Voelter, “A convenient approach to the synthesis of triazols
bearing sugar moieties” 13th European Carbohydrate Symposium, Bratislava, Slovakia, August
21-26, 2005.
5. Raid J. Abdel-Jalil, M. Uebele, W. Ehrlichmann, Wolfgang Voelter, Hans-Jurgen Machulla, “1-
[18F]Fluoroethyleneglycol-2-nitroimidazoles, a novel class of potential hypoxia PET markers”,
International Symposium on Trends in Radiopharmaceuticals (ISTR-2005)”, Vienna, Austria,
14-18 November, 2005.
6. Raid J. Abdel-Jalil, Hans-Jurgen Machulla and Wolfgang Voelter, “A novel and efficient
cyclization access to optically of pure 1,4,5,6-tetrahydro-as-trizines, fused to carbohydrate”, 12th
European Carbohydrate Symposium
, Grenoble, France, July 6-11, 2003.
7. T. Toyokuni, J. C. Walsh, R. J. Abdel-Jalil, A. Dominguez, J. E. Shively, N. Satyamurthy, J. R.
Barrio, M. E. Phelps, A. M. Wu, and S. S. Gambhir, “Synthesis of a New Maleimide-Containing
Thiol-Reactive 18F-Labeling Agent, N-{4-[(4-
[18F]Fluorobenzylidene)aminooxy]butyl}maleimide, and its Application to the Labeling of an
Oligodeoxynucleotide. 48th Annual Meeting • Society of Nuclear Medicine, Toronto, Ontario,
Canada, 2001.
8. R. J. Abdel-Jalil, J. C. Walsh, J. L. Stone, J. E. Shively, N. Satyamurthy, J. R. Barrio, M. E.
Phelps, A. M. Wu, S. S. Gambhir, and T. Toyokuni, ” Synthesis of 4-[(4-
[18F]Fluorobenzylidene)aminooxy]butyl Vinyl Sulfone as an Amine- and Thiol-Reactive 18F-
Labeling Agent”, 48th Annual Meeting • Society of Nuclear Medicine, Toronto, Ontario, Canada,
2001.
9. R. J. Abdel-Jalil, Raed Al-qauasmeh, Peter Heeg, Mustafa El-Abadelah, Salim Sabri and
Wolfgang Voelter," Synthesis and Properties of 6-Flouro-7-(1-Methyl-4-
piperazinyl)quionoxalines", 7th Ibn Sina International Conference on Pure and Applied
Heterocyclic Chemistry
, P-148, Alexandria-Egypt. 2000.
10. R. J. Abdel-Jalil, Monther Khanfar, Mustafa El-Abadelah, Salim Sabri, Samer Al-Gharabli and
Wolfgang Voelter, " Facile Synthesis of Pyrazolo[3,4-d]pyramidine-7-one Derivatives", 7th Ibn
Sina International Conference on Pure and Applied Heterocyclic Chemistry
, P-147,
Alexandria-Egypt. 2000.
11. R. J. Abdel-Jalil, Wolfgang Voelter, " An expeditious approach to tri-substituted chiral
thiazolines", The 10th European Carbohydrate Symposium, PA 079, Galway, Ireland 1999.
12. R. J. Abdel-Jalil, Wolfgang Voelter, " A stereospecific synthesis of N-substituted chiral
morpholines", The 10th European Carbohydrate Symposium, PA 080, Galway, Ireland
1999.
13. R. J. Abdel-Jalil, R. A. Al-Qawasmeh, W. Voelter, "A Stereospecific Synthesis of Tetra-
Substituted Chiral Piperazines", The 19th International Carbohydrate Symposium, BP020 San
Diego, USA. 1998.
14. R. J. Abdel-Jalil, R. A. Al-Qawasmeh, W. Voelter, "(4→4)-Di(2,3-anhydropentopyranosides), a
Novel Class of Potential Enzyme Inhibitors", The 19th International Carbohydrate
Symposium
, BP167 San Diego, USA 1998.
15. R. J. Abdel-Jalil, R. A. Al-Qawasmeh Y. Al-Abed, W. Voelter, The 9th European
Carbohydrate Symposium, A170, Utrecht, Netherlands 1999.
16. R. J. Abdel-Jalil, Y. Al-Abed, R. A. Al-Qawasmeh, W. Voelter, The 9th European
Carbohydrate Symposium, A171, Utrecht, Netherlands 1999.
Personal Data

Source: http://www.squ.edu.om/Portals/75/staff/Academic/CV/Raid%20CV.pdf

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