Department of Environmental Toxicology University of California, Davis 4330 Meyers Hall One Shields Avenue Davis, CA 95616 Tel: (530)-752-4380 Email: lma@ucdavis.edu Education Ph.D. in Analytical Chemistry, Xiamen University, 2002 M.S. in Applied Chemistry, Shanxi University, 1999 B.S. in Physical Chemistry, Shanxi University, 1996 Research Experience Nov. 2005 – Present Biochemical mechanisms of oxidative stress signal transduction pathways. Postdoctoral researcher, Dept. of Environmental Toxicology; Laboratory of Dr. Matthew J. Wood, University of California, Davis. Aug. 2003 – Oct. 2005 Solution NMR characterization of structure and dynamics of Heme proteins. Postdoctoral researcher, Dept. of Biophysics and Biochemistry; Laboratory of Dr. Gerd N. La Mar, University of California, Davis. Sep. 2002 – Jun. 2003 Hydrogen Peroxide Biosensor. Visiting Scholar of Chemistry in the laboratory of Dr. Martin M.M. Choi. Hong Kong Baptist University, SAR, P.R. China. Sep. 1999 – Jun. 2002 Molecular recognition and chemical sensing based on the intramolecular charge transfer (ICT) dual fluorescence dialkylaminobenzoic acid. Graduate research of Analytical Chemistry in the laboratory of Dr. Yun-Bao Jiang, Xiamen University, P.R. China 361005. Sep. 1996 – Jul. 1999 NMR studies on β-Cyclodextrin inclusion complexes. Graduate research of Physical Chemistry in the laboratory of Prof. Liang Chen, Shanxi University, P.R. China 030006. Honors and Awards
1995 Honor of Excellent Student of Shanxi University 1995 “Bao-Cheng Niu Fellowship” of undergraduate, Shanxi University 1999 “M.S. Thesis Scholarship” of graduate research, Shanxi University 2000 “Powerlong Scholarship”, Xiamen University and Powerlong Industry Inc. td. 2001 “Northpole Fellowship”, Xiamen University 2002 Honor of Excellent Student of Xiamen University Publications 1. L.H. Ma, Y. Liu, X. Zhang, T. Yoshida and G.N. La Mar (2006) Solution 1H NMR characterization of the
electronic structure of the azide-inhibited complex of the protohemin complex of N. meningitidis heme
Curriculum Vitae Li-Hua Ma
oxygenase: A low-spin orbital ground state determined by the axial azide rather than His ligand, in preparation.
2. Y. Liu, L.H. Ma, T. Yoshida, J.D. Satterlee, and G.N. La Mar (2006) The influence of hemin vinyl→methyl
substitution on the interaction between the C-terminus and substrate and the "aging" of the heme oxygenase from N. meningitidis. Induction of active site structural heterogeneity by a two-fold symmetric hemin. J. Am. Chem. Soc., submitted.
3. L.H. Ma, Y. Liu, X. Zhang, T. Yoshida and G.N. La Mar (2006) 1H NMR study of the magnetic properties
and electronic structure of the hydroxide complex of the substrate-bound heme oxygenase from N. meningitidis. Influence of the axial water deprotonation on the distal H-bond network. J. Am. Chem. Soc., in press.
4. L.H. Ma, Y. Liu, X. Zhang, T. Yoshida, K.C. Langry, K.M. Smith and G.N. La Mar (2006) Modulation of the
Axial Water Hydrogen-Bonding Properties by Chemical Modification of the substrate in Resting State, Substrate-Bound Heme Oxygenase from N. Meningitidis; Coupling to the Distal H-Bond Network via Ordered Water Molecules. J. Am. Chem. Soc., in press.
5. Y. Liu, L.H. Ma, J.D. Satterlee, T.Yoshida and G.N. La Mar (2006) Reorganization of the C-terminus
interaction with substrate and the induction of an active site structural heterogeneity upon replacing the native hemin vinyls with methyls in the heme oxygenase from N.meningitides. Biochemistry., in press.
6. L.H. Ma, M.F. Choi (2004) Application of a Datalogger in Biosensing: A Reagentless Hydrogen Peroxide
Biosensor. J. Chem. Edu., 81, 862-864.
7. L.H. Ma, Z.B. Chen, Y.B. Jiang (2003) Intramolecular charge transfer with 4-(N-phenylamino)benzoic acid:
the N-phenyl amino conjugation effect. Chem. Phys. Lett., 372, 104-113.
8. W. Huang, X. Zhang, L.H. Ma, Y.B. Jiang (2002) Intramolecular charge transfer dual fluorescence of
substituted-phenyl p-dimethylaminobenzoates with comparable electron acceptors. Chem. Phys. Lett., 352, 401-407.
9. X. Zhang, L.H. Ma, X.Y. Sun, C.J. Wang, Z. Li, Y.B. Jiang (2002) Direct spectroscopic evidence for the
excited-state charge transfer with anilino substituted benzanilides in non-polar solvent cyclohexane. Chem. J. Chinese Univ., 23, 1130-1132.
10. L.H. Ma, Z.C. Wen, L.R. Lin, Y.B. Jiang (2001) Dual fluorescence of naphthylamines in alkaline aqueous
solution. Chem. Phys. Lett., 346, 423-429.
11. F.Y. Wu, L.H. Ma, Y.B. Jiang (2001) Fluorescence sensing of anions based on a novel dual fluorescent
neutral receptor N-(4-dimethylamionbenzoyl)thiourea. Anal. Sci., 17, 801-803.
12. L.H. Ma, Z.C. Wen, X.Y. Sun, Y.B. Jiang (2001) Dual fluorescence of 1-aminonaphthalene in aqueous
solutions of high pH: Acidic dissociation of N-H bond. Chem. J. Chinese Univ., 22, 1125-1127.
13. L.H. Ma, Z.C. Wen, X.Y. Sun, Y.B. Jiang (2000) Excited state intramolecular charge transfer and electron
transfer in N-(1-naphthyl) aminoacetic acid. Chem. J. Chinese Univ., 21, 1377-1379.
14. L. Chen, L.H. Ma, D.P. Meng (2000) Chiral discrimination by modified cyclodextrins. Analysis and Testing Technology and Instruments, 6, 129-134.
15. L. Chen, J.B. Chao, L.H. Ma (2000) The NMR studies on Norfloxacin with HP-β-CD inclusion complexes. Chinese Journal of Magnetic Resonance, 17, 203-210.
Curriculum Vitae Li-Hua Ma 16. L.H. Ma, L. Chen, S.P. Huang (1999) Fluorescence study on Phenothiazine and its halogenate derivatives. Spectroscopy and Spectral Analysis, 19, 250-252.
17. L.H. Ma, L. Chen, S.P. Huang (1999) Fluorescence studies on Amoxicilin. Spectroscopy and Spectral
18. S.P. Huang, L.H. Ma, L. Chen (1997) Fluorescence spectra study on 2,3,7,8-tetra-chloro-N-ethyl
phenothiazine. Spectroscopy and Spectral Analysis, 17, 112-114.
19. S.P. Huang, L. Chen, L.H. Ma (1997) Study on fluorescence method of Pefloxacin. Spectroscopy and
Book Chapters
1. Y.B. Jiang, L.R. Lin, X.Y. Sun, L.H. Ma, Z.C. Wen, C.H. Liu (2000) Designing sensing system of pH
fluorescence sensor. In “Chemo- and Biosensors and their Assemblies in Ocean Graphic Monitoring”, Xiamen University Press, pp114-126.
References
Dr. Matthew J. Wood Department of Environmental Toxicology University of California, Davis Davis, CA 95616 Phone 1-530-754-2271 Email mjwood@ucdavis.edu Dr. Gerd N. La Mar Department of Chemistry University of California, Davis Davis, CA 95616 Phone 1-530-752-8995 Email lamar@chem.ucdavis.edu Dr. Yun-Bao Jiang Department of Chemistry Xiamen University PR China Phone 86-592-2185662 Email ybjiang@xmu.edu.cn Prof. Liang Chen Test and Analysis Center Shanxi University PR China Phone 86-351-7018079 Email Liangchen1945@gmail.com
RE51-ALTERACIONES EN LA VASCULATURA OVÁRICA EN PACIENTES CON ALTA Y BAJA RESPUESTA A Scotti L1, Abramovich D1, Pascuali N1, Haro Durand L1, Bisioli C2, de Zúñiga I2, Tesone M1, Parborell F1. 1Instituto de Biología y Medicina Experimental (IByME-CONICET); 2PREGNA Medicina Reproductiva. RE54- ASOCIACION DE GLIPR1L1/GLIPR1L2 AL ESPERMATOZOIDE Y SU PARTICIPACION EN EL PROCESO DE FERTILIZACIÓN.
HCRS 230 Pharmacology for the Health Professional Description: This course presents the components of pharmacology including techniques of administration, dosage calculations, foundations of pharmacology, patient education, health promotion, and a detailed overview of each drug class and commonly used drugs by body system. Pharmacology is an integral part of every aspect of health caree