Consultation Response Form SCENIHR preliminary report on
“The safety of dental amalgam and alternative dental restoration materials for patients and users” References / Literature Case number: 517159724081705308 Due to rare space on the online form we send our literature references in addition to our consultation response. Literature European Academy for Environmental Medicine
1. Adams et al. Mercury, lead, and zinc in baby teeth of children with autism
Ask et al. Inorganic mercury and methylmercury in placentas of Swedish
3. Ask K et al. (2002) Inorganic Mercury an Methylmercury in Placentas of
Swedish Women, Enviromental Health Perspectives, 110 (5), 523 – 526.
4. Baasch E (1964), Theoretische Überlegungen zur Ätiologie der Sclerosis
multiplex, Archiv für Neurologie, Neurochirurgie und Psychiatrie 98, 1 – 19.
5. Bagenstose LM et al. (1998) IL-12 Down-Regulates Autoantibody Production
in Mercury-Induced Autoimmunity, J Immunol, 160, 1 – 16.
6. Barregard L et al. (2007) Renal Effects of Dental Amalgam in Children: the
New England Childrenûs Amalgan Trial, Environ Health Perspect 10504 online 23 Nov. 2007, 1 – 5.
7. Bartram et al. (2006) Die Bedeutung von Epikutantestungen und
Lymphozytentransformationstest für die Diagnostik von Typ IV-Sensibilisierungen. Stellungnahme des Deutschen Berufsverbandes der Umweltmediziner. J Lab Med, 30(2), 101-106.
8. Berlin M. Mercury in dental-filling materials – an updated risk analysis in
environmental medical terms. An overview of scientific literature published in 1997-2002 and current knowledge. 2003.
9. Bigazzi PE (1999) Gold-Induced Renal Autoimmunity, Mercury-Induced
Renal Autoimmunity, Conclusions, Environ Health Perspect, 107 (S5), 1 –33.
10. Bigazzi PE (2008) Metals and Kidney Autoimmunity, ehp Volume 116, Nr. 2:
11. Björnberg et al. Transport of methylmercury and inorganic mercury to the
fetus and breast-fed infant. Env. Health Persp 2005
EUROPEAN ACADEMY FOR ENVIRONMENTAL MEDICINE e.V. - Enrolled in the Register of Societies and Associations – Amtsgericht Würzburg VR 2055 - First Chairman: Dr. Kurt E. Müller – Managing Chairmann: Dr. Peter Ohnsorge - Public-minded and nonprofit-making objects in accordance with the „Tax Privileged Objects“ of the German tax code. - Banking-account: 43812841 Sparkasse Mainfranken: BLZ 790 500 00 - IBAN: DE 36 7905 0000 0043 812841 – SWIFT-BIC:BYLADEM1SWU
12. Black RS et al. (1979) Influence of Silver, Mercury, Lead, Cadmium, and
Selenium on Glutathione Peroxidase and Transferase Activities in Rats. Mological Trace Elem Res 1, 313-324.
13. Boadi et al. In vitro exposure to mercury and cadmium alters term human
placental membrane fluidity. Toxicol Appl Pharm 1992
14. Bradstreet et al. A Case-Control Study of Mercury Burden in Children with
Autistic Spectrum Disorders. J Amer Phys and Surg 2003
15. Burrows D (1986) Hypersensitivity to mercury, nickel an chromium in relation
to dental materials, Intern Dent J, 36, 30 – 34.
16. Cheuk Wong. Attention-deficit hyperactivity disorder and blood mercury level:
a case-control study in Chinese children. Neuropediatrics 2006 Aug;37(4):234-40
17. Clark R et al. (1972) Statistische Untersuchung zur Frage der Kreuzallergie
bei Metallsalzen, ??? Heft 5/1972: 222 – 239.
18. Clarkson TW (2002) The three modern faces of mercury. Environ Health
19. Clarkson TW et al. (1972) The Transport of Elemental Mercury into Fetal
Tissues, Bio. Neonate, 21, 239 – 244.
20. Clarkson TW et al. (1985) Reproductive an developmental toxicity of metals,
Scand J Work Environ Health, 11, 145 – 154.
21. Counter. Mercury exposure in children:a review. Toxicol Appl Pharm 2004
22. Cox NH et al. (1988) Thiomersal allergy and vaccination reactions, Contact
23. Da Costa et al. Breast-milk mercury concentrations and amalgam surface in
mothers from Brasília Biol Trace Elem Res 2005
24. Davis BJ et al. (2001) Mercury Vapor and Female Reproductive Toxicity,
Toxicological Sciences 59, 291 – 296.
25. Drasch et al. Mercury in human colostrum and early breast milk. Its
dependence on dental amalgam J Trace Elem Med Biol 1998
26. Drasch et al. Mercury burden of human fetal and infant tissues. Eur J Pediatr
27. Drasch G et al. (1997) Einfluß von Amalgamfüllungen auf die Quecksilber-
konzentration in menschlichen Organen. Deutsch Zahnärztl Z 47, 490-496.
28. Drasch et al. (1997) Are blood, urine, hair and muscle valid bio.monitoring
parameters for the internal burden of men with heavy metals mercury, lead and cadmium? Trace Elem Electrolytes 14, 116-123.
29. Drasch G et al. (2000) The Mt. Diwata study on the Philippines 1999 –
assessing mercury intoxication of the population by small scale gold mining. Sci Total Environ 267, 151-168.
30. Drasch G et al. (2002) Scientific comment on the German human biological
monitoring values (HBM values) for mercury. Int. J Environ Health 205, 509-512.
31. Egglestone DW et al. (1987) Correlation of dental amalgam with mercury in
brain tissue. J Prosthet Dent 58, 704-707.
32. Eggleston DW et al. (1987), Correlation of dental amalgam with mercury in
brain tissue, Research and Education, 58 (6), 704 – 707.
33. Eggleston DW et al. (1987) Correlation of dental amalgam with mercury in
34. Frank I et al. (2000) Immuntoxikologie chronischer Quecksilberbelastung,
Zeitsch Umweltmed, 8 (2), 94 – 100.
35. Godfrey ME et al. (2003) Apolipoprotein E genotyping as a potential
biomarker for mercury neurotoxicity. Journal of Alzheimerûs Discease, 5, 189 – 195.
36. Gundlach P (1979) Neurologische Aspekte der Quecksilbervergiftung eine
Literarische Übersicht, Inaugural-Dissertation München 1979.
37. Hahn LJ et al. 1990 Dental „silver“ tooth fillings: a source of mercury
exposure revealed by whole-body image scan tissue analysis. FASEB.J 3, 2641-2646.
38. Hahn LJ et al. 1990 Dental „silver“ tooth fillings: a source of mercury
exposure revealed by whole-body image scan tissue analysis. FASEB.J 3, 2641-2646.
39. Hassan AN et al. (1999) Humoral Assessment of Neurotoxicity and Auto
Mechanisms, Environ Health Persp, 107 (5), 1 – 26.
40. Hoeper M (2003) Signaling Molecules in Pulmonary Hypertension, N Engl J
41. Holmes AS (2006) Chelation of Mercury for the Treatment of Autism,
42. Kalveram KJ et al. (1973) Misleading patch test results with aluminum Finn
chambers an mercury salts, Contact Dermatitis. 1973: 219 – 221.
43. Kantarjian AD (??) A Syndrome clinically resembling amyotrophic lateral
sclerosis following chronic mercurialism, 639 – 644
44. Klein CL et al. (1994) The role of metal corrosion in inflammatory processes:
induction of adhesion molecules by heavy metal ions, Journal of meterails science: Materials in Medicine, 5, 798 – 807.
45. Klein CL et al. (1995) Comparative studies on cytotoxic effects of dental
amalgams an alternative alloys according to ISO standards in vitro, Journal of Materials Science: Materials in Medicine, 6, 708 – 714.
46. Lammers HJ (2003) Autismus durch Quecksilberbelatung? Zeitschrift für
47. Leistevuo J et al. (2001) Dental Amalgam Fillings and the Amount of organic
Mercury in Human Salivia. Caries Res 35, 163-166.
48. Lorscheider FL et al. (1991) Mercury exposure from „silver“ fillings. Lancet
49. Lorscheider FL et al. (1995) Mercury exposure from „silver“ tooth fillings:
emerging evidence questions a traditional dental Paradigm. FASEB J 9, 504-508.
50. Marquard H, Schäfer SG (1997) Lehrbuch der Toxikologie, Spektrum
Akademischer Verlag, Heidelberg, Berlin, p. 530.
51. Mauch E et al. (1995) Trace metals in multiple sclerosis, Neurology.
Psychiatry and Brain Research, 149 – 154.
52. Miura K et al. (1995) Mercury Toxicity in Goyer RA et al. Toxicology of
metals. Springer, Berlin, Heidelberg, New York, London, 163-187.
53. Müller KE (2002) BfArM verfolgt Strategien der Vergangenheit. Zeitsch f
54. Müller KE et al. (1997) Szintigraphie der dopaminergen D2-Rezeptoren bei
Belastung durch Xenobiotika, Ökol. Ärztebl. 1, 28-31.
55. Müller KE (2003) Zwei Episonden eines Guillain-Barré-Syndrom (GBS) nach
Roxithromycin und Mercurius solubilis, umg, 16 (2), 101 – 102.
56. Müller KE (2004) Immuntoxikologie der Metalle, umg, 17 (4), 299 – 301.
57. Muss C et al. (2000) Untersuchungen zur immunsuppressiven Wirkung von
Dentallegierungen unter Verwendung von Recall-Antigenen – eine Praxisstudie, Zeitsch Umweltmed, 4, 228 – 233.
58. Mutter J et al. (2004) Amalgam studies: disregarding basic principels of
mercury toxicity. Int J Hyg Environ Health 207, 391-397.
59. Mutter J et al. (2004) Alzheimer Disease: Mercury as pathogenetic factor an
apolipoprotein E as a moderator, Neuroendocrinol Lett 2004, 331 – 339.
60. Mutter J et al. (2006) Quecksilber und Autismus: Zunehmende Beweise?
Umwelt-medizin-gesellschaft 1/2006, 53 – 60.
61. Mutter J et al. (2004) Alzheimer Disease: Mercury as pathogenetic factor an
apolipoprotein E as a moderator, Neuroendocrinol Lett 2004: 275 – 283.
62. Nylander M (1986) Mercury in pituitary glands of dentists. Lancet 1, 442.
63. Pelletier L et al. (1995) Immunotoxicology of Metals in Goyer RA et al.
Toxicology of Metals, Springer, Berlin, Heidelberg, New York, London, p 77 –87.
64. Pizzichini M et al. (2002) Release of mercury from dental amalgam and its
nfluence on salivary antioxidant activity. Sci Total Environ 284, 19-25.
65. Powell JJ et al. (1999) Evidence for the role of Encironmental Agents in the
Initiation or Progression of Autoimmune Conditions, Environ Health Perspect, 107 (S5), 667 – 670.
66. Reichel F.X. et all (2007) Taschenatlas der Pharmakologie und Toxikologie
für Zahnmedizin, Georg-Thieme-Verlag, Stuttgart
67. Rowley B et al. (2004) Mechanisms of heavy metal-induced autoimmunity,
Molecular Immunology, 42, 833 – 838.
68. Siblerud RL et al. (1994) Evidence that mercury from silver dental fillings may
be an etiological factor in multiple sclerosis, The Science of the Total Environment 142, 191 – 205.
69. Siblerud RL et al. (1992) A Comparison of mental Health of mulitple sclerosis
patients with silver/mercury dental fillings an those with fillings removed, Psychological reports, 1139 – 1151.
70. Stejskal J et al. (1999) The role of metals in autoimmunity an the link to
neuroendocrinology, Neuroendocrinol Letters, 20, 351 – 364.
71. Stejskal V et al. (1995) Mercury-Specific Lymphocytes: An Indication of
Mercury Allergy in Man, J Clin Immun, 16 (1),31 – 40.
72. Sterzl I et al. (1999) Mercury and nickel allergy: risk factors in fatigue an
autoimmunity, Neuroendocrinol Letters, 20, 221 – 228.
73. Stewart WF et al. (2002) ApoE Genotype, Past Adult lead exposure, and
Neurobehavioral Function, Enviromental Health Perspectives Volume 110, 501 – 505.
74. Uversky V et al. (2004) Metal-triggered Structural Transformations,
Aggregation, an Fibrillation of Human Synuclein, J Biol Chem, 276 (47),1 –28.
75. Valentine-Thon E et al. (2005) Metallsensibilisierung: Nachweis, Validierung
und Verlaufskontrolle mittels Lymphozytentransformations-Test (LTT-MELISA), Zs.f. Orthomol.Med., 1, 12 – 15.
76. Valentine-Thon et al. (2003) Validity of MELISA for metal sensitivity testing,
Neuroendocrinol Letters, 24, 57 – 64.
77. Vimy M et al. (1990) Maternal-fetal distribution of mercury (203Hg) released
fro dental amalgam fillings. Am J Physiol 258, R939-945.
78. Warfvinge K et al. (2006) Systemic autoimmunity due to mercury vapor
exposure in genetically susceptible mice: dose-response studies. Toxicol Appl Pharmacol 132 (2), 299-309.
79. Weiner JA et al. (1993) The relationship between mercury concentration in
human organs and different predictor variables. Sci Total Environ 138, 101-115.
80. WHO (1990) Environmental Health Criteria 118: Inorganic Mercury. World
81. WHO/OMS. Inorganic mercury. Environmental Health Criteria 118, IPCS
82. Wojcik DP et al. (2006) Mercury toxicity presenting as chronic fatigue,
memory impairment an depression, Neuroendocrinol Lett 2006, 415 – 423.
83. Yamane Y (1977) Suppressive effect of zinc on the toxicity of mercury. Chem
84. Yannai S et al. (1991) Transformationn of Inorganic Mercury by Candida
albicans and Saccharomyces cerevisiae. Appl Environm Mocrobiol 57:1, 245-247.
85. Yoshida M (2002), Placental to Fetal Transfer of Mercury and Fetotoxicity,
86. Ziemba SE et al. (2005) Inorganic Mercury Inhibits the Activation of LAT in T-
Cell Receptor-Mediated Signal Transduction, Toxicological Sciences, 89 (1), 145 – 153.
Curriculum Vitae Neil A Martinson Postal Address 27 Illovo Rd Emmarentia 2195 SOUTH AFRICA Tel: +27823316756 Email: martinson@hivsa.com Educational Qualifications University of the Witwatersrand, Johannesburg, School of Public Health, Johns Hopkins University, Board certification as a Family Physician Employment History June 2002-present Deputy Director Perinatal HIV Resear
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