Le métronidazole (Flagyl) reste la référence dans le traitement des infections anaérobies et des parasitoses comme la giardiase ou l’amibiase. Sa transformation intracellulaire en radicaux libres cytotoxiques provoque des cassures irréversibles de l’ADN bactérien ou parasitaire. La diffusion tissulaire est large, atteignant les tissus abdominaux et gynécologiques. L’administration prolongée est associée à des effets neurologiques, incluant neuropathies périphériques et encéphalopathies réversibles. L’association avec l’alcool déclenche une réaction de type antabuse. Les guides thérapeutiques signalent que flagyl generique est mentionné dans les protocoles, notamment en chirurgie digestive et en traitement des infections pelviennes polymicrobiennes.

Microsoft word - residual.doc

MATERIAL SAFETY DATA SHEET
SECTION 1 - PRODUCT IDENTIFICATION AND USE
PRODUCT IDENTIFICATION
IDENTIFIER: RESIDUAL
NUMBER (PIN):
PRODUCT USE: Residual Crawling Insecticide
WHMIS CLASS: PCP #18094

MANUFACTURER’S
SUPPLIER’S
NAME: GP CHEMICALS SPECIALTY LTD.
STREET ADDRESS:
STREET ADDRESS: 55 West Beaver Creek Road, Unit 10
PROVINCE:
CITY: Richmond Hill
PROVINCE: Ontario
EMERGENCY
EMERGENCY M-F 8am-5pm
PHONE NO:
CODE: L4B 1K5
PHONE NO : (416) 229-9717
SECTION 2 - HAZARDOUS INGREDIENTS
HAZARDOUS INGREDIENTS
LD5O OF INGREDIENTS
LC5O OF INGREDIENT
(SPECIFY SPECIES AND
(SPECIFY SPECIES)
ROUTE) RAT ORAL
RABBIT ORAL
Permethrin
52645-53-1
>2500mg/kg-Oral (Rat)
Pyrethrins
8003-34-7
1680mg/kg-Oral (Rat)
N-Octyl Bicycloheptene Dicarboximide
113-48-4
4980mg/kg-Oral (Rat)
4080 mg/l Inhal (Rat)
Odourless Mineral Spirits
64742-47-8
>5000mg/kg-Oral (Rat)
Isobutane
520,000 ppm(2Hr) Inhal
Mouse
SECTION 3 - PHYSICAL DATA
PHYSICAL STATE:
ODOUR AND APPEARANCE: Clear liquid with low odour.
TOTAL VOC %: N/D
VAPOUR PRESSURE
VAPOUR DENSITY
EVAPORATION
BOILING POINT
FREEZING POINT
of Can (psig @ 20ºC):
(AIR=1): >1
(° C) ~188C ( ° C)
SPECIFIC GRAVITY(H2O
SOLUBILITY IN WATER:
=1) @22 ºC: 0.75
SECTION 4 - FIRE AND EXPLOSION DATA
FLAMMABILITY (as per Flame Projection Test): Extremely flammable Spray
MEANS OF EXTINCTION: Foam, CO2, Dry Media.
FLASHPOINT ( ° C) (of concentrate only):
UPPER FLAMMABLE LIMIT:
LOWER FLAMMABLE
( % BY VOLUME)
LIMIT(% BY VOLUME)

SPECIAL FIRE FIGHTING PROCEDURES :
Wear self-contained breathing apparatus and protective clothing. Cool fire
exposed containers to prevent rupturing.
UNUSUAL FIRE AND EXPLOSION HAZARDS: SENSITIVITY TO IMPACT:
SENSITIVITY TO STATIC
Exposure to temperatures above 50 C may cause
DISCHARGE:
bursting.
SECTION 5 – REACTIVITY DATA
STABILITY
Material Stable
INCOMPATIBILITY: Avoid contact with strong oxidizing agents.
HAZARDOUS POLYMERIZATION:
HAZARDOUS DECOMPOSITION PRODUCTS:
Will not occur.
Carbon Dioxide, Carbon Monoxide.
SECTION 6- TOXICOLOGICAL PROPERTIES
ROUTE OF ENTRY:
SKIN CONTACT
SKIN ABSORPTION
EYE CONTACT
INHALATION
INGESTION
EFFECTS OF ACUTE EXPOSURE TO PRODUCT: Eye contact: May cause slight irritation but does not injure eye tissue. Skin
contact: Frequent or prolonged contact may cause irritation. Inhalation: Inhalation of mist can cause irritation of nasal and
respiratory passages. Abusive or excessive inhalation may cause irritation to the upper respiratory tract, dizziness, nausea and
other central nervous system effects. Ingestion: Can cause gastrointestinal irritation, nausea, vomiting and diarrhea. Aspiration
of material into the lungs can cause chemical pneumonitis. Minimal toxicity.
EXPOSURE LIMITS:
IRRITANCY OF PRODUCT: SENSITIZATION TO
CARCINOGENICITY: Non-
PRODUCT:
Hazardous
TERATOGENICITY: N/D
REPRODUCTIVE
MUTAGENICITY: N/D
SYNERGISTIC MATERIAL:
EFFECTS: N/D
SECTION 7 – PREVENTATIVE MEASURES
PERSONAL PROTECTIVE EQUIPMENT:
PROTECTIVE GLOVES: None
RESPIRATORY PROTECTION:
EYE PROTECTION: None needed
needed for proper use in accordance with
None needed for proper use in
unless it is anticipated that a splash or
label directions. Use chemical resistant
accordance with label directions.
spray back will occur, then wear safety
gloves if hand contact will be made.
glasses or chemical proof goggles.
FOOTWEAR: (SPECIFY)
CLOTHING: (SPECIFY)
OTHER: (SPECIFY)
VENTILATION: Provide local exhaust to keep TLV of Section II ingredients below acceptable limits.
LEAK AND SPILL PROCEDURE: Allow propellent to evaporate. Keep sparks, heat sources and open flame far away from
spill or leak. Cover with absorbent material and sweep up. Wash area with water to prevent slipping.
WASTE DISPOSAL: Consult federal, provincial and local authorities regarding approved disposal procedures.
HANDLING PROCEDURES AND EQUIPMENT: Keep away from heat, open flame and sparks. No smoking.
STORAGE REQUIREMENTS: Store in a cool, dry area away from heat or open flame. Do not store at temperatures above
50C. KEEP OUT OF REACH OF CHILDREN.
SPECIAL SHIPPING INFORMATION:
24 HOUR EMERGENCY SERVICE CANUTEC - (613) 996-6666 (COLLECT)
LEGEND: N/D = Not Determined N/A = Not Applicable < = Less Than >=More Than
SECTION 8 – FIRST AID MEASURES
EYES: Flush eyes with water for at least 15 minutes. Seek medical attention immediately.
SKIN: Wash with soap and water.
INHALATION: Remove to fresh air. Seek medical attention if necessary.
INGESTION: Give two glasses of water . Do not induce vomiting. Seek medical attention immediately.
SECTION 9 - PREPARATION DATE OF MSDS
PREPARED BY (GROUP, DEPARTMENT, ETC.)
SUPERSEDE MSDS DATED:
GP Chemicals Specialty Ltd
September 5, 2013
December 22, 2011
The information provided in this Material Safety Data Sheet has been obtained from sources believed to be reliable. The supplier provides no warranties expressed or implied and assumes no responsibility for the accuracy or the completeness of the data contained herein.

Source: http://www.gpchemicals.ca/pdf/insecticides/residual.pdf